Research progress of exploring the healing mechanism of traditional Chi-nese medicine on postoperative anal fistula based on immune regulation
Anal fistula is an infectious disease with perianal hardness,recurrent rupture and pus flow,itching as the main clinical manifestations.Surgery is the main treatment method.Traditional Chinese medicine treatment of postoperative wound healing of anal fistula is clinically effective,can effectively control wound infection,regulate the body's immune function,reduce postoperative complications,promote the growth of granulation tissue,so as to achieve the effect of eliminating swelling and eliminating blood stasis,convergence of sores and muscle growth.However,Chinese medicine treatment of postoperative wound healing of anal fistula still exists in a single research method,insufficient research on the mechanism of action and other problems.In this paper,we describe the mechanisms of inflammatory factors,growth factors,signaling pathways,immunoglobulins and matrix metalloproteinases affecting postoperative wound healing after anal fistula surgery,aiming to provide a reliable theoretical basis and new ideas for basic research and clinical practice.
Traditional Chinese medicineAnal fistulasImmune regulationWound healingMechanismOverview