Effect of Dexmedetomidine combined with ultrasound-guided caudal epidural block on the clinical results of preschoolers undergoing hydrocele of spermatic cord operation
Objective To observe the effect of Dexmedetomidine combined with ultrasound-guided caudal epidural block on the clinical results of preschoolers undergoing hydrocele of spermatic cord operation.Methods From May 2022 to April 2023,fifty preschoolers who performed hydrocele of spermatic cord operation in Xianfeng County People's Hospital,Hubei Province were enrolled,they were divided into Dexmedetomidine group and control group by random number table method,with 25 cases in each group.The Dexmedetomidine group was induced and maintained with Sevoflurane,and 0.4 μg/kg Dexmedetomidine was pumped within 10-15 min after the intravenous was established,then ultrasound-guided caudal block was performed,while the control group was treated with alternative normal saline.The heart rate(HR),mean arterial pressure(MAP),and respiratory rate(Res)at enter the operating room(T0),caudal epidural block(T1),skin incision(T2),the end of surgery(T3),recovery(T4),and 5 min after recovery(T5)were compared between two groups;the scores of pediatric anesthesia emergence delirium(PAED),Ramsay sedation,and the Children's Hospital of Eastern Ontario pain scale(CHEOPS)at T4,15 min after recovery(T6),and 30 min after recovery(T7)were compared between two groups;the occurrence of relevant adverse events between two groups were recorded.Results There were significant differences in HR time,intergroup,and interaction between two groups(P＜0.05).There were significant differences in MAP and Res at time paints(P＜0.05);there were no significant differences in MAP and Res intergroup and interaction between two groups(P＞0.05).Inter-group comparison:at T2-T5,there were significant differences in HR between two groups(P＜0.05).At T0-T1,there were no significant differences in HR between two groups(P＞0.05).At T0-T5,there were no significant differences in MAP and Res between two groups(P＞0.05).Overall comparison:there were statistically significant differences in the scores of PAED and Ramsay sedation time and inter-group between two groups(P＜0.05).There was no significant difference in the interaction of the scores of PAED and Ramsay sedation between two groups(P＞0.05).There were statistically significant differences in the score of CHEOPS time,inter-group,and interaction between two groups(P＜0.05).Intra-group comparison:at T4,T6,and T7,there were statistically significant differences in the scores of PAED,Ramsay sedation,and CHEOPS between the two groups(P＜0.05).Inter-group comparison:at T4,T6,and T7,the scores of PAED,Ramsay sedation,and CHEOPS were compared between two groups,and the differences were statistically significant(P＜0.05).There was no significant difference in the total incidence of adverse reactions between two groups(P＞0.05).Conclusion Dexmedetomidine combined with ultrasound-guided caudal epidural block can be safely applied in preschoolers undergoing hydrocele of spermatic cord operation,reduce recovery agitation,and get better sedative and analgesic.
DexmedetomidineUltrasound-guidedCaudal epidural blockHydrocele of spermatic cordPreschoolers
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