Predictive value of arterial blood lactate combined with serum amyloid A levels for the occurrence of shock in children patients with sepsis
Objective To explore the predictive value of arterial blood lactate(Lac)combined with serum amyloid A(SAA)levels for the occurrence of shock in children with sepsis.Methods A retrospective analysis was conducted on medical records of 92 children patients with sepsis admitted to Hefei Second People's Hospital from January 2020 to January 2023.They were divided into shock group and conversion group based on the occurrence of septic shock during fluid resuscitation.The influencing factors of the occurrence of shock in children patients with sepsis were screened,and the efficacy of arterial blood Lac and SAA in predicting the occurrence of shock in children patients with sepsis was evaluated.Results Among the 92 children patients with sepsis,38 cases(41.30%)progressed to septic shock.The arterial blood Lac,SAA,and pediatric sequential organ failure assessment(pSOFA)scores in shock group were higher than those in conversion group,while Glasgow coma scale(GCS)score in shock group was lower than that in conversion group(P＜0.05).Arterial blood Lac(OR=3.601),SAA(OR=3.688),pSOFA score(OR=3.579),and GCS score(OR=0.254)were the influencing factors for occurrence of shock in children patients with sepsis(P＜0.05).The area under the curve of the single and combined prediction of arterial Lac and SAA for occurrence of shock in children patients with sepsis were 0.794,0.809,and 0.884,respectively.Conclusion The expression levels of arterial blood Lac and SAA are related to the occurrence of shock in children patients with sepsis,and they are effective in predicting the occurrence of shock in children patients with sepsis.
SepsisShockChildren patientBlood lactateSerum amyloid A
NETL
NSTL
万方数据
