首页|基于数据挖掘探讨全仁夫教授治疗强直性脊柱炎用药规律

基于数据挖掘探讨全仁夫教授治疗强直性脊柱炎用药规律

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目的 探讨全仁夫教授治疗强直性脊柱炎(AS)的用药规律。方法 筛选整理 2020 年 8 月至 2022 年 1 月在杭州市萧山区中医院全仁夫教授门诊治疗AS患者的临床处方,运用中医传承计算平台(V3。0)分析药物频次、性味、归经及功效,并采用关联规则、聚类分析对组方规律进行挖掘。结果 本研究共收录处方85首,涉及药物116种,其中高频中药 26味,药性以温性为主,药味以甘、辛、苦味居多,药物主入肝、肾、脾经,药物功效主要为祛风湿类和补虚类。得出常用药物模式 14个及关联性用药组合 20个,分析获得聚类处方组合 4个。结论 全仁夫教授治疗AS的用药规律为祛风湿与补肝肾并用,标本兼治;主张温督散寒、行气活血;同时重视补养脾胃。
Discussion on the medication rules of Professor Quan Renfu in the treat-ment of ankylosing spondylitis based on data mining
Objective To investigate the medication rules of Professor Quan Renfu in the treatment of ankylosing spondylitis(AS).Methods The clinical prescriptions of AS patients treated by Professor Quan Renfu in Hangzhou Xiaoshan District Hospital of Traditional Chinese Medicine from August 2020 to January 2022 were screened and sorted out.The Traditional Chinese Medicine Inheritance Computing Platform(V3.0)was used to analyze drug frequency,nature,flavour,channel tropism,and efficacy,and association rules and cluster analysis were used to explore the rules of prescription composition.Results A total of 85 prescriptions were included in this study,involving 116 kinds of drugs,including 26 kinds of high-frequency traditional Chinese medicine.The drug natures were mainly warm.The drug flavours were mainly sweet,pungent,and bitter.Drugs mainly entered the liver,kidney,and spleen channels.The main efficacy of the drug was to dispel wind-dampness and tonifying deficiency.A total of 14 commonly used drug patterns and 20 associated drug combinations were obtained,and four cluster prescription combinations were obtained by analysis.Conclusion Professor Quan Renfu's treatment of AS medication rules are to dispel wind-dampness and tonifying liver and kidney,giving consideration to both manifestation and root cause;advocating warming governor vessel dispersing cold,activating qi and activating blood,and paying attention to nourishing the spleen and stomach at the same time.

Ankylosing spondylitisTraditional Chinese Medicine Inheritance Computing SystemData miningMedication rulesQuan Renfu

辛大伟、罗淦、裘世杰

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杭州市萧山区中医院骨科,浙江杭州 311201

强直性脊柱炎 中医传承计算平台 数据挖掘 用药规律 全仁夫

浙江省名老中医专家传承工作室建设项目浙江省中医药科技计划

GZS20200362018ZB111

2024

中国医药导报
中国医学科学院

中国医药导报

CSTPCD
影响因子:1.759
ISSN:1673-7210
年,卷(期):2024.21(9)
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