Analysis of the application of dual laser protocol in non-perfusion area and macular area in patients with macular edema secondary to branch retinal vein occlusion
Objective To investigate the application of dual laser protocol in non-perfusion area and macular area in patients with macular edema(ME)secondary to branch retinal vein occlusion(BRVO).Methods According to the random number table method,150 patients with BRVO secondary ME admitted to Lishui People's Hospital of Zhejiang Province from May 2021 to May 2022 were divided into control group(intravitreal injection treatment of Ranibizumab)and dual laser group(Ranibizumab combined with dual laser treatment of non-perfusion area and macular area),with 75 cases each.Three months after treatment,the clinical effects of the two groups were compared,and the recovery conditions(best corrected visual acuity[BCVA],intraocular pressure[IOP],central macular thickness[CMT]),macular blood flow,and fluorescein fundus angiography results were compared.Results The effect of dual laser group was better than that of control group(P＜0.05).At three months after treatment,BCVA in both groups were higher than those before treatment,IOP,CMT in both groups were lower than those before treatment,and BCVA of dual laser group were higher than those of control group,IOP and CMT were lower than those of control group(P＜0.05).At three months after treatment,the blood density of shallow and deep capillary in both groups were higher than those before treatment,and those of dual laser group were higher than those of control group(P＜0.05).The incidences of cystoid leakage,diffuse leakage,and local leakage in dual laser group were all lower than those in control group(P＜0.05).Conclusion Intravitreal injection of Ranibizumab combined with dual laser in non-perfusion area and macular area in the treatment of BRVO secondary ME can improve the therapeutic effect of Ranibizumab,promote visual recovery of patients,improve blood flow in macular area,and reduce the occurrence of vascular leakage.
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