首页|抗生素联合益生菌在下颌阻生智齿拔除术后患者中的应用效果

抗生素联合益生菌在下颌阻生智齿拔除术后患者中的应用效果

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目的 探究抗生素联合益生菌在下颌阻生智齿拔除术后的应用效果.方法 选取2021年1月至2023年 1 月在安徽省六安市人民医院口腔科行下颌阻生智齿拔除术的患者 82 例,按照随机数字表法将其分为对照组和观察组,每组41例.对照组术后给予阿莫西林克拉维酸钾(4 d),观察组在对照组的基础上使用益生菌辅助治疗(益生菌使用时间 7d,阿莫西林克拉维酸钾使用时间 4d).比较两组术后 7、14、21 d的疼痛及胃肠道症状、手术部位感染、并发症发生情况.结果 两组术后 14、21 d的数字评定量表(NRS)评分均低于术后 7d,术后 21d低于术后14 d(P<0.05).观察组术后 7、14、21 d的NRS评分均低于同期对照组(P<0.05).观察组的胃症状、肠道症状、腹泻发生率均低于对照组(P<0.05).两组均未见手术部位感染.两组的肿胀、发热、张口困难、出血发生率比较,差异无统计学意义(P>0.05).结论 下颌阻生智齿拔除手术后,采用抗生素联合益生菌可有效降低术后疼痛,应用效果显著,值得推广.
Application effect of antibiotics combined with probiotics in patients with mandibular impacted wisdom tooth extraction
Objective To explore the application effect of antibiotics combined with probiotics in mandibular impacted wisdom tooth extraction.Methods A total of 82 patients undergoing mandibular impacted wisdom tooth extraction in Department of Stomatology,People's Hospital of Lu'an City,Anhui Province from January 2021 to January 2023 were selected and divided into control group and observation group according to random number table method,with 41 cases in each group.The control group was given Amoxicillin Clavulanate Potassium(4 d)after surgery,and the observation group was given probiotics based on the control group(probiotics for 7 d,Amoxicillin Clavulanate Potassium for 4 d).The pain and gastrointestinal symptoms,surgical site infection,and complications were compared between the two groups at 7,14,and 21 d after surgery.Results The numerical rating scale(NRS)scores of 14 and 21 d after surgery were lower than those of 7 d after surgery,and those of 21 d after surgery were lower than those of 14 d after surgery(P<0.05).The NRS scores of the observation group at 7,14,and 21 d after surgery were lower than those of the control group at the same time points(P<0.05).The incidence of gastric symptoms,intestinal symptoms,and diarrhea in the observation group was lower than that in the control group(P<0.05).No surgical site infection was found in both groups.There was no significant difference in the incidence of swelling,fever,mouth opening difficulty,and bleeding between the two groups(P>0.05).Conclusion After mandibular impacted wisdom tooth extraction,antibiotics combined with probiotics can effectively reduce postoperative pain,and the application effect is significant,worthy of promotion.

AntibioticsProbioticsMandibular impacted wisdom tooth extraction

张宏波、王元银

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安徽医科大学附属六安医院口腔科,安徽六安 237005

安徽医科大学附属口腔医院口腔颌面外科,安徽合肥 230032

抗生素 益生菌 下颌阻生智齿拔除术

安徽省科技厅重点研发项目

201904a07020062

2024

中国医药导报
中国医学科学院

中国医药导报

CSTPCD
影响因子:1.759
ISSN:1673-7210
年,卷(期):2024.21(9)
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