Experience summary of Professor Yu Chenghui in treating immunoglob-ulin G4-related kidney diseases
The clinical manifestations of immunoglobulin G4(IgG4)-related diseases are heterogeneous and easy to be misdiagnosed.In the kidneys,IgG4-related diseases are often characterized by membranous nephropathy,renal interstitial fibrosis,or retroperitoneal fibrosis resulting in urinary tract obstruction.Professor Yu Chenghui is a famous expert in the treatment of integrative Chinese and Western medicine in Jiangsu Province,and has unique insights in the treatment of kidney disease.Professor Yu believes that the pathogenesis of IgG4 related kidney disease is based on the deficiency of the spleen and kidney qi,combined with liver depression and qi stagnation,which could cause accumulation of phlegm and blood stasis.In terms of treatment,differentiation and treatment should be based on the different clinical manifestations of patients.The pathogenesis of IgG4 related membranous nephropathy is mostly spleen and kidney qi deficiency,and internal stagnation of water and dampness,and the treatment mainly focuses on nourishing the body,removing blood stasis,and clearing the kidney.Renal interstitial fibrosis is characterized by the combination of dampness heat,phlegm turbidity,blood stasis,and other pathogenic factors on the basis of spleen and kidney deficiency,with dampness as the cause,it is a miniature abdominal mass disease,and the treatment should focus on resolving dampness on the basis of tonifying the kidney and spleen.Retroperitoneal fibrosis is characterized by liver stagnation and qi stagnation,as well as the accumulation of phlegm and blood stasis,and it is a abdominal mass disease with tangible symptom.In terms of treatment,attention should be paid to regulating liver qi while resolving phlegm,removing blood stasis,and dispersing stasis.
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