Predictive value of dynamic contrast enhancement magnetic resonance imaging nomogram for lymphovascular invasion in rectal cancer
Objective To evaluate the value of dynamic contrast enhancement magnetic resonance imaging(DCE-MRI)quantitative parameters in the assessment of lymphovascular invasion(LVI)of rectal cancer.Methods The clinical data of 79 patients with rectal cancer hospitalized in Tongde Hospital of Zhejiang Province from January 2019 to December 2022 were retrospectively analyzed.According to the pathological results,they were divided into LVI negative group and LVI positive group.The clinicopathological features of two groups were compared;quantitative parameters of DCE-MRI(volume transfer constant[Ktrans],extravascular extracellular space volume percentage value[Ve],and rate constant[Kep]),and apparent diffusion coefficient(ADC)were compared between two groups;the influencing factors of LVI positive were analyzed;and receiver operating characteristic curve was used to evaluate the predictive efficiency of each parameter model.Results A total of 79 patients,46 cases were LVI negative,and 33 cases were LVI positive.There were significant differences in pathological T stage,pathological N stage,and length diameter between two groups(P＜0.05).The values of Ktrans,Kep,and Ve in LVI positive group were higher than those in LVI negative group(P＜0.05);there was no significant difference in ADC values between two groups(P＞0.05).Ktrans(OR=143.46)and Ve(OR=50.92)were LVI positive risk factors for rectal cancer(P＜0.05).The area under the curve value predicted by the nomogram for LVI positive rectal cancer was higher than that of Ve(P＜0.05).Calibration curve showed that the nomogram had better predictive power for LVI of rectal cancer.Conclusion The nomogram constructed by DCE-MRI quantitative parameters Krans and Ve values has important value in predicting LVI of rectal cancer.
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