摘要
目的 分析超声联合血清内皮抑素(ES)评估甲状腺癌患者经口腔前庭入路腔镜甲状腺手术后复发的价值.方法 选取江苏省海安市中医院2019年12月至2021年12月收治的116例经口腔前庭入路腔镜甲状腺手术患者为观察组,选取同期109名健康体检者为参照组.比较两组超声最大流速(Vmax)、血流阻力指数(RI)及血清ES,绘制受试者操作特征曲线分析超声联合血清ES水平对术后复发的评估效能.结果 观察组Vmax、RI、血清ES水平均高于参照组(P＜0.05).术后复发组Vmax、RI、血清ES均高于术后未复发组(P＜0.05).Vmax、RI、ES均是术后复发的危险因素(OR＞1,P＜0.05).超声和血清ES联合预测术后复发的曲线下面积高于单独评估.结论 Vmax、RI、血清ES水平均为术后复发的危险因素,超声评估效能高.
Abstract
Objective To evaluate the value of ultrasound combined with serum endostatin(ES)in the evaluating of recurrence after endoscopic thyroid surgery through oral vestibular approach in patients with thyroid cancer.Methods A total of 116 thyroid surgery patients admitted to Haian Hospital of Traditional Chinese Medicine in Jiangsu Province from December 2019 to December 2021 were selected as the observation group,and 109 healthy physical examination subjects during the same period were selected as the reference group.Ultrasound maxmum velocity(V max),blood flow resistance index(RI),and serum ES were compared between the two groups,and receiver operating characteristic curve was drawn to analyze the efficacy of ultrasound combined with serum ES level in evaluating postoperative recurrence.Results Vmax,RI,and serum ES levels in the observation group were higher than those in the reference group(P＜0.05).Vmax,RI,and serum ES in the recurrence group were significantly higher than those in the non-recurrence group(P＜0.05).Vmax,RI,and serum ES were risk factors for postoperative recurrence(OR＞1,P＜0.05).The area under curve of combined ultrasound and serum ES predict postoperative recurrence was higher than those of single evaluation(P＜0.05).Conclusion Vmax,RI,and serum ES levels are risk factors for postoperative recurrence,and ultrasound evaluation is higher.
基金项目
江苏省自然科学基金青年基金(BK20180195)
NETL
NSTL
万方数据