Diagnostic value of creatine kinase isoenzyme-MB,cardiac troponin Ⅰ,and N-terminal pro-brain natriuretic peptide in non-ST segment eleva-tion myocardial infarction
Objective To explore the diagnostic value of creatine kinase isoenzyme-MB(CK-MB),cardiac troponin Ⅰ(cTnI),and N-terminal pro-brain natriuretic peptide precursor(NT-pro BNP)in non-ST segment elevation myocardial infarction.Methods A total of 120 patients with non-ST segment elevation myocardial infarction admitted to Rugao People's Hospital of Jiangsu Province from June 2020 to January 2022 were selected as observation group,and another 120 patients with unstable angina pectoris were selected as control group.The electrocardiogram characteristics of patients with non-ST segment elevation myocardial infarction were observed;the levels of CK-MB,cTnI,and NT-pro BNP were compared between two groups;the factors influencing the occurrence of non-ST elevation myocardial infarction were analyzed;and receiver operating characteristic curve was used to analyze the diagnostic efficacy of CK-MB,cTnI,and NT-pro BNP in the diagnosis of non-ST elevation myocardial infarction.Results In 120 patients with non-ST segment elevation myocardial infarction,ST segment depression was sustained in 53 cases and dynamic ST segment depression was developed in 67 cases.The serum levels of CK-MB,cTnI,and NT-pro BNP in observation group were higher than those in control group(P＜0.05).CK-MB,cTnI,and NT-pro BNP were the risk factors for non-ST elevation myocardial infarction(OR=3.515,4.683,3.577,P＜0.05).The area under the curve of CK-MB,cTnI,and NT-pro BNP for single and combined diagnosis of acute non-ST elevation myocardial infarction were 0.750(95％CI:0.649-0.851),0.748(95％CI:0.649-0.847),0.731(95％CI:0.631-0.832),and 0.827(95％CI:0.739-0.915)respectively.Conclusion CK-MB,cTnI,and NT-pro BNP can be used to assist in the diagnosis of non-ST elevation myocardial infarction,and the diagnostic efficiency is high.
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