Prognostic value of serum pentraxin 3 and C-reactive protein for postop-erative infection after pediatric intussusception surgery
Objective To explore the predictive value of serum pentraxin 3(PTX3)and C-reactive protein(CRP)for post-operative infection after pediatric intussusception surgery.Methods A total of 112 children who underwent intussusception surgery treated in Nantong Maternal and Child Health Care Hospital,Jiangsu Province from January 2019 to December 2022 were selected as study objects.The incidence of postoperative infection was observed and the children were divided into in-fected group and non-infected group.Clinical data were collected,and levels of serum PTX3 and CRP were detected.The risk factors of postoperative infection in children treated with intussusception surgery were analyzed;the predictive value of PTX3 combined with CRP in postoperative infection in children treated with intussusception surgery was evaluated by re-ceiver operating characteristic(ROC)curve.Results Postoperative infection occurred in 31 cases(27.68％)of 112 children who underwent intussusception surgery.The age of infected group was lower than that of non-infected group,hospital stay was longer than that of non-infected group,and the proportion of conversion to laparotomy,levels of PTX3,and CRP were higher than those of non-infected group(P＜0.05).Conversion to laparotomy(OR=2.615),CRP(OR=2.343),and PTX3(OR=2.112)were independent risk factors for postoperative infection in children treated with intussusception surgery(P＜0.05).The areas under the curve of PTX3,CRP,and their combination in predicting postoperative infection in children treated with intussusception surgery were 0.749,0.712,and 0.918,respectively.Conclusion Serum PTX3 and CRP are independent risk factors for postoperative infection in children treated with intussusception surgery.PTX3 combined with CRP is a better predictor of postoperative infection in children treated with intussusception surgery.
Pediatric intussusception surgeryPostoperative infectionPentraxin 3C-reactive proteinPredictive value
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