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直径<10 mm结直肠息肉发生高危腺瘤的风险因素分析

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目的 探讨直径<10 mm结直肠息肉发生高危腺瘤的相关风险因素.方法 选取2019年10月至2021年3月解放军总医院第一医学中心和解放军总医院海南医院接受结肠镜检查的患者作为研究对象.根据腺瘤数量和病理特征,将患者分为高危腺瘤组和非高危腺瘤组.分析高危腺瘤发生的风险因素.结果 本研究共1 267例患者纳入统计分析,其中高危腺瘤组341例(26.9%),非高危腺瘤组926例(73.1%).高危腺瘤组的年龄(45~<75岁)、男性、饮酒史、吸烟史、频繁食用腌制食品、高盐饮食、慢性病史、结直肠息肉史及最大息肉直径(>5~<10mm)占比高于非高危腺瘤组(P<0.05).年龄(45~<75岁)、男性、高盐饮食、偶发肛门坠胀、慢性病史,及最大息肉直径(>5~<10 mm)为高危腺瘤发生的危险因素(OR>1,P<0.05).结论 年龄(45~<75岁)、男性、高盐饮食、偶发肛门坠胀、慢性病史,及最大息肉直径(>5~<10mm)是直径<10 mm结直肠息肉高危腺瘤发生的影响因素,为内镜医师评估风险及有针对性应用"切除和丢弃策略"提供了基础.
Analysis of risk factors for colorectal polyps<10 mm in diameter with high-risk adenoma
Objective To investigate the risk factors of colorectal polyps<10 mm in diameter with high-risk adenoma.Methods Patients who underwent colonoscopy in the First Medical Center of Chinese People's Liberation Army General Hospital and Hainan Hospital of Chinese People's Liberation Army General Hospital from October 2019 to March 2021 were selected as study objects.According to the number of adenomas and pathological features,the patients were divided into high-risk adenoma group and non-high-risk adenoma group.The risk factors of high-risk adenoma were analyzed.Results A total of 1 267 patients were included in the study,including 341 patients(26.9%)in the high-risk adenoma group and 926 patients(73.1%)in non-high-risk adenoma group.The proportion of age(45-<75 years old),male,drinking history,smoking history,frequent consumption of pickled food,high salt diet,chronic history,history of colorectal polyp,and maximum polyp diameter(>5-<10 mm)in high-risk adenoma group was higher than those in non-high-risk adenoma group(P<0.05).Age(45-<75 years),male,high salt diet,occasional anal distention,chronic history,and maximum polyp diameter(>5-<10 mm)were risk factors for high-risk adenomas(OR>1,P<0.05).Conclusion Age(45-<75 years),male,high salt diet,occasiontal anal distention,chronic history,and maximum polyp diameter(>5-<10 mm)are risk factors for colorectal polyps<10 mm with high-risk adenomas,providing a basis for endoscopists to assess the risk and apply targeted"resect and discard strategy".

Colorectal polypsColonic neoplasmsRisk factorsResect-and-discard strategy

张瀚文、吴俊嶺、赵志壮、陈怡、栾哲、孙刚

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解放军总医院第一医学中心消化内科,北京 100080

解放军总医院海南医院老年医学科,海南三亚 572013

结直肠息肉 结肠肿瘤 风险因素 切除和丢弃策略

国家自然科学基金中国人民解放军总医院青年自主创新科学基金

3217089822QNFC058

2024

中国医药导报
中国医学科学院

中国医药导报

CSTPCD
影响因子:1.759
ISSN:1673-7210
年,卷(期):2024.21(11)
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