Objective To investigate the effect of Qinghuang Granules on neonatal jaundice.Methods A total of 144 children with neonatal jaundice admitted to Shandong Provincial Third Hospital from January to December 2021 were selected,and they were divided into control group and observation group by random number table method,with 72 cases in each groups.The control group was given blue light treatment,and observation group was combined with Qinghuang Granules oral on the basis of control group,and the treatment period was five days.The clinical effect of two groups was compared;serum total bilirubin,direct bilirubin,indirect bilirubin,immunoglobulin(Ig)A,IgG,and jaundice index were compared between two groups before and after treatment;the duration of jaundice resolution,the duration of blue light treatment,the cost of blue light treatment,and the length of hospital stay were compared between two groups;and the occurrence of adverse reactions during treatment was recorded in both groups.Results The clinical effect of observation group was better than that of control group(P＜0.05).After treatment,the levels of total bilirubin and indirect bilirubin in two groups were lower than those before treatment,and those of observation group were lower than those of control group(P＜0.05);there were no significant differences in the levels of direct bilirubin between two groups before and after treatment(P＞0.05).After treatment,the levels of IgA and IgG were higher than those before treatment,and those of observation group were higher than those of control group(P＜0.05).After treatment,the jaundice index of two groups were lower than those before treatment,and those of observation group were lower than those of control group(P＜0.05).The duration of jaundice resolution,the duration of blue light treatment,and the length of hospital stay in observation group were shorter than those in control group,and the cost of blue light treatment was lower than that in control group(P＜0.05).The total incidence of adverse reactions in observation group was lower than that in control group(P＜0.05).Conclusion Qinghuang Granules has a good clinical effect,so it is considered to be applied in the treatment of neonatal jaundice in order to promote the outcome of the disease.
Neonatal jaundiceJaundice indexQinghuang GranulesImmune function
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