首页|氯己定含漱液辅助正畸压低治疗对牙周炎患者炎症水平及心理状态的影响

氯己定含漱液辅助正畸压低治疗对牙周炎患者炎症水平及心理状态的影响

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目的 探讨氯己定含漱液辅助正畸压低治疗对牙周炎患者炎症水平及心理状态的影响.方法 选取2019年2月至2022年2月中国人民解放军联勤保障部队第九○四医院收治的92例牙周炎患者作为研究对象,按照随机数字表法将其分为对照组和研究组,各46例.对照组予以正畸压低治疗,研究组予以正畸压低联合氯己定含漱液治疗.治疗2周后,比较两组的疗效、牙周状态、疼痛程度、炎症因子、心理状态.随访1年,记录患者复发结局.结果 研究组临床疗效优于对照组(P<0.05).治疗前,两组探针深度、牙龈附着丧失、白细胞介素-6、前列腺素E2水平及焦虑自评量表、抑郁自评量表评分比较,差异无统计学意义(P>0.05);治疗2周后,两组探针深度、牙龈附着丧失、白细胞介素-6、前列腺素E2水平及焦虑自评量表、抑郁自评量表评分均低于治疗前,且研究组低于对照组(P<0.05).整体分析发现:视觉模拟评分(VAS)组间、时间点比较及交互作用差异均有统计学意义(P<0.05).组内比较:两组治疗1周后VAS评分均低于治疗前,两组治疗2周后VAS评分均低于治疗前、治疗1周后(P<0.05).组间比较:治疗1、2周后,研究组VAS评分低于对照组(P<0.05).研究组复发率低于对照组(P<0.05).结论 氯己定含漱液辅助正畸压低治疗牙周炎有助于抑制炎症反应,缓解疼痛,降低负面情绪,效果良好.
Effect of Chlorhexidine Gargle assisted orthodontic depression treatment on the inflammation level and psychological status of patients with peri-odontitis
Objective To explore the effect of Chlorhexidine Gargle assisted orthodontic depression treatment on the inflammation level and psychological status of patients with periodontitis.Methods Ninety-two patients with periodontitis admitted to the 904th Hospital of Chinese People's Liberation Army Joint Logistics Support Force from February 2019 to February 2022 were selected as the research subjects.They were divided into the control group and the study group by using the random number table method,with 46 cases in each group.The control group received orthodontic depression treatment,while the study group received orthodontic depression combined with Chlorhexidine Gargle treatment.Two weeks after treatment,the efficacy,periodontal status,pain level,inflammatory factors,and psychological status between two groups were compared.Follow up for one year,the patient's recurrence outcome was recorded.Results The clinical efficacy of study group was better than that of control group(P<0.05).Before treatment,there were no statistically significant differences between two groups in terms of probe depth,loss of gingival attachment,interleukin-6,prostaglandin E 2,self-rating anxiety scale,and self-rating depression scale(P>0.05).Two weeks after treatment,the probe depth,gingival attachment loss,interleukin-6 and prostaglandin E2 levels,as well as self-rating anxiety scale and self-rating depression scale scores in two groups were lower than those before treatment,and study group was lower than that control group(P<0.05).Overall analysis found that there were statistically significant differences in visual analogue scale(VAS)between groups,time point comparisons and interaction effects(P<0.05).Intra group comparison:VAS scores of two groups one week after treatment were lower than those before treatment,and VAS scores of two groups two weeks after treatment were lower than those before treatment and one week after treatment(P<0.05).Inter group comparison:after treatment for one and two weeks,VAS score of study group was lower than that of control group(P<0.05).The recurrence rate in study group was lower than that in control group(P<0.05).Conclusion Chlorhexidine Gargle assisted orthodontic depression in the treatment of periodontitis can help suppress inflammatory reactions,alleviate pain,reduce negative emotions,and have good therapeutic effects.

PeriodontitisOrthodontic depressionChlorhexidine GargleInflammationRecrudescence

王洁、王飞、顾玲娟、程玮

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中国人民解放军联勤保障部队第九○四医院口腔科,江苏无锡 214000

牙周炎 正畸压低 氯己定含漱液 炎症 复发

江苏省自然科学基金

BK20220198

2024

中国医药导报
中国医学科学院

中国医药导报

CSTPCD
影响因子:1.759
ISSN:1673-7210
年,卷(期):2024.21(12)
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