首页|血液复合参数中性粒细胞与淋巴细胞比值对老年突发性聋患者预后的预测价值

血液复合参数中性粒细胞与淋巴细胞比值对老年突发性聋患者预后的预测价值

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目的 探讨入院中性粒细胞与淋巴细胞比值(NLR)对老年突发性耳聋患者预后的预测价值.方法 选取2019年2月至2021年7月在南京医科大学康达学院第一附属医院耳鼻咽喉头颈外科就诊的147例老年突发性聋患者为研究对象,根据预后情况将其分为预后良好组(104例)与预后不良组(43例).收集研究对象的年龄、既往病史、血液检测指标等,比较两组一般资料,并进行多因素logistic回归与受试者操作特征曲线分析.结果 预后不良组年龄、NLR和血小板与淋巴细胞比值高于预后良好组(P<0.05);年龄(OR=1.154,95%CI:1.059~1.259)、听力损失(OR=2.668,95%CI:1.393~5.113)、NLR(OR=1.719,95%CI:1.223~2.417)为老年突发性聋预后的影响因素.NLR曲线下面积为0.837,灵敏度和特异度分别为88.37%、69.23%,截断值为4.23.结论 NLR可作为老年突发性聋预后评估的可靠指标,有一定的临床应用价值.
Value of blood composite parameters neutrophil-to-lymphocyte ratio to prognosis predictions in the elderly patients with sudden deafness
Objective To explore the value of prognosis predictions neutrophil-to-lymphocyte ratio(NLR)in elderly patients with sudden deafness.Methods A total of 147 elderly patients with sudden deafness treated in the Department of Otolaryngology,and Head and Neck Surgery,the First Affiliated Hospital of Kangda College of Nanjing Medical University from February 2019 to July 2021 were selected as the study objects,according to the prognosis,they were divided into the good prognosis group(104 cases)and the poor prognosis group(43 cases).The age,past history,and blood test indexes of the subjects were collected,and the general data of the two groups were compared,and multivariate logistic regression and receiver operating characteristic curve analysis were performed.Results Age,NLR,and platelet to lymphocyte ratio in poor prognosis group were higher than those in good prognosis group(P<0.05).Age(OR=1.154,95%CI:1.059-1.259),hearing loss(OR=2.668,95%CI:1.393-5.113),NLR(OR=1.719,95%CI:1.223-2.417)were the prognostic factors of sudden deafness in the elderly.The area under of curve of the NLR was 0.837,the sensitivity and specificity were 88.37%and 69.23%,respectively,and the truncation value was 4.23.Conclusion The NLR value contributed the most to prognosis predictions,which might be of practical clinical value in elderly patients with sudden deafness.

Sudden deafnessPrognosis assessmentNeutrophil-to-lymphocyte ratioEldedy patients

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南京医科大学康达学院第一附属医院耳鼻咽喉头颈外科,江苏连云港 222000

突发性聋 预后评估 中性粒细胞与淋巴细胞比值 老年

2024

中国医药导报
中国医学科学院

中国医药导报

CSTPCD
影响因子:1.759
ISSN:1673-7210
年,卷(期):2024.21(12)
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