首页|基于脉搏波和心电信号的无创连续血压预测方法研究

基于脉搏波和心电信号的无创连续血压预测方法研究

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目的 研究基于脉搏波和心电信号的无创连续血压预测方法。方法 从MIMIC-Ⅲ数据库中选取300个病例,用于构建血压预测模型、模型验证;另收集2022年1月至6月入住福建省立医院重症监护病房的121例患者,用于测试模型;采集患者动脉血压、光电容积脉搏波和心电图信号。构建两个血压预测模型,一个是以人工提取出的8种特征参数构建的人工特征参数模型,另一个是以8种特征参数加1种卷积神经网络提取的特征进行融合构建的特征融合模型。对两个预测模型进行验证、测试,评价指标采用平均绝对误差(MAE)、标准差(SD)、均方根误差(RMSE),根据国际公认的美国医疗器械促进协会(AAMI)规定的标准进行评价,对比两个模型预测能力。结果 用MIMIC-Ⅲ数据对两个模型进行评价,特征融合模型的MAE、SD符合AAMI标准,RMSE比人工特征参数模型低。用实际收集的重症患者数据对两个模型进行评价,特征融合模型收缩压的SD、舒张压的MAE和SD达到AAMI标准,RMSE也比人工特征参数模型低。结论 特征融合模型的预测能力比人工特征参数模型好。
Method study of non-invasive continuous blood pressure prediction based on pulse wave and electrocardiosignal
Objective To study the non-invasive continuous blood pressure prediction method based on pulse wave and electrocardiosignal.Methods A total of 300 cases were selected from MIMIC-Ⅲ database to build blood prediction model and model verification.Meanwhile,121 cases were collected which were hospitalized in the Intensive Care Unit of Fujian Provincial Hospital from January to June 2022 for test model.The arterial blood pressure,photoplethysmography,and electrocardiography signal of patients were collected.Two blood pressure prediction models were built.The first one was artificial feature parameter model that was built based on eight artificially collected feature parameters.One was feature fusion model that was fused and built based on the eight feature parameters and the other one feature collected from convolutional neural network.These two prediction models were verified and tested.The evaluation indexes applied mean absolute error(MAE),standard deviation(SD),and root mean square error(RMSE).Evaluation was proceeded according to the internationally recognized specified standard of(Association for the Advancement of Medical Instrumentation,AAMI)to compare the predictive ability of both models.Results MIMIC-Ⅲ data were applied to evaluate both models.The MAE and SD of feature fusion model were consistent with the standard of AAMI.RMSE was lower than it of artificial feature parameter model.The actual collected data of critical patients were applied to evaluate.The SD of systolic pressure,MAE,and SD of diastolic pressure of feature fusion model met the standard of AAMI.RMSE was also lower than that of artificial feature parameters.Conclusion The predictive ability of feature fusion model is better than artificial feature parameter models.

PhotoplethysmographyElectrocardiogramFusion featureNon-invasive continuous blood pressure predictionWearable blood pressure equipment

张健春、王量弘、庄丽媛、张炜鑫、王新康

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福建省立医院心电诊断科,福建福州 350001

福州大学物理与信息工程学院,福建福州 350108

福建医科大学省立临床医学院,福建福州 350001

光电容积脉搏波 心电图 融合特征 无创连续血压预测 可穿戴式血压设备

国家自然科学基金福建省卫生教育联合科技攻关计划福建医科大学启航基金

619711402019-WJ-182020QH1187

2024

中国医药导报
中国医学科学院

中国医药导报

CSTPCD
影响因子:1.759
ISSN:1673-7210
年,卷(期):2024.21(13)
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