Correlation of blood glucose and glycosylated hemoglobin with lesion grading and visual impairment of patients with diabetic retinopathy
Objective To explore the relationship between the levels of blood glucose and glycosylated hemoglobin(HbA1c)and the pathological grading and visual impairment of patients with diabetic retinopathy(DR).Methods A total of 100 patients diagnosed with diabetes in Branch of Huaian First People's Hospital of Jiangsu Province from January 2019 to December 2022 were selected,including 60 DR patients(DR group)and 40 no diabetic retinopathy(NDR)patients(NDR group).According to DR staging standard,the DR group was divided into 35 patients with non-proliferative DR(NPDR group)and 25 patients with proliferative DR(PDR group).The levels of blood glucose and HbA1c were compared be-tween DR group and NDR group,NPDR group and PDR group,and the the degree of visual impairment among patients with different levels of fast-ing plasma glucose(FPG),2 h postprandial plasma glucose(2hPG),and HbA1c were compared.The correlation of FPG,2hPG,HbA1c with visual imoairment and lesion grading was analyzed.Results The levels of FPG,2hPG,bedtime blood glucose,and HbA1c in the NDR group were lower than those in the DR group(P＜0.05).The levels of FPG,2hPG,bedtime blood glucose,and HbA1c in the NPDR group were lower than those in the PDR group(P＜0.05).There were statistically significant differences in the degree of visual impairment among patients with different levels of FPG,2hPG,and HbA1c(P＜0.05).The levels of FPG,2hPG,and HbA1c were positively correlated with visual acuity and lesion grading(r＞0,P＜0.05).Conclusion Levels of blood glucose and HbA1c are correlated with the occurrence,lesion grading,and visual impairment of DR.As blood glucose and HbA1c levels increase,the degree of visual impairment in DR patients increases.
万方数据
维普
