中国医药导报2024,Vol.21Issue(13) :113-115,119.DOI:10.20047/j.issn1673-7210.2024.13.28

基于磁共振第2.1版前列腺影像报告和数据系统评分联合游离PSA/总PSA在前列腺癌早期诊断中的价值

Value of prostate imaging reporting and data system version 2.1 based on magnetic resonance combined with free PSA/total PSA in early diagnosis of prostate cancer

杨星星 顾峰 陆健美 吕杨
中国医药导报2024,Vol.21Issue(13) :113-115,119.DOI:10.20047/j.issn1673-7210.2024.13.28

基于磁共振第2.1版前列腺影像报告和数据系统评分联合游离PSA/总PSA在前列腺癌早期诊断中的价值

Value of prostate imaging reporting and data system version 2.1 based on magnetic resonance combined with free PSA/total PSA in early diagnosis of prostate cancer

杨星星 1顾峰 1陆健美 1吕杨1
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作者信息

  • 1. 江苏省南通市第二人民医院放射科,江苏南通 226000
  • 折叠

摘要

目的 探究基于磁共振第2.1版前列腺影像报告和数据系统(PI-RADS V2.1)评分联合游离前列腺特异性抗原(PSA)/总PSA在前列腺癌早期诊断中的价值.方法 筛选2018年6月至2022年6月江苏省南通市第二人民医院收诊的82例早期前列腺癌患者为癌变组;另选取同期收诊的82例良性前列腺增生症患者为良性组.收集两组血清PSA检测结果、磁共振扫描结果等,分析早期前列腺癌发生的影响因素;评估游离PSA/总PSA和PI-RADSV2.1评分对早期前列腺癌的诊断效能.结果 癌变组总PSA水平高于良性组,游离PSA/总PSA低于良性组(P<0.05).癌变组移行带PI-RADS V2.1评分高于良性组(P<0.05).总PSA、游离PSA/总PSA、移行带PI-RADS V2.1评分是早期前列腺癌发生的影响因素(P<0.05).游离PSA/总PSA、移行带PI-RADS V2.1评分联合诊断早期前列腺癌的曲线下面积高于各指标单独检测.结论 游离PSA/总PSA、PI-RADS V2.1可用于辅助诊断早期前列腺癌,且诊断效能良好.

Abstract

Objective To explore the value of prostate imaging reporting and data system version 2.1(PI-RADS V2.1)based on magnetic reso-nance combined with free prostate specific antigen(PSA)/total PSA in early diagnosis of prostate cancer.Methods A total of 82 patients with early prostate cancer admitted to Nantong Second People's Hospital,Jiangsu Province between June 2018 and June 2022 were screened as canceration group;and 82 patients with benign prostatic hyperplasia admitted at the same time were selected as benign group.Serum PSA test results and magnetic resonance scan results were collected in two groups,and the influencing factors of early prostate cancer were analyzed;the diagnostic efficacy of free PSA/total PSA and PI-RADS V2.1 scores for early prostate cancer were evaluated.Results The total PSA level of canceration group was higher than that of benign group,while the free PSA/total PSA was lower than that in benign group(P<0.05).The PI-RADS V2.1 score in transition zone of canceration group was higher than that of benign group(P<0.05).Total PSA,free PSA/total PSA,and PI-RADS V2.1 score in transition zone were influencing factors for early prostate cancer(P<0.05).The area under the curve of free PSA/total PSA and PI-RADS V2.1 in transition zone in the diagnosis of early prostate cancer was higher than that of each indicator alone.Conclusion Free PSA/total PSA and PI-RADS V2.1 can be used to assist in the diagnosis of prostate cancer,and their diagnostic efficacy is well.

关键词

前列腺/前列腺特异性抗原/磁共振/第2.1版前列腺影像报告和数据系统/诊断

Key words

Prostate/Prostate specific antigen/Magnetic resonance/Prostate imaging reporting and data system version 2.1/Diagnosis

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基金项目

江苏省卫生健康委科研项目(Z2020061)

出版年

2024
中国医药导报
中国医学科学院

中国医药导报

CSTPCD
影响因子:1.759
ISSN:1673-7210
参考文献量24
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