The prognosis of patients with primary liver cancer is poor due to its easy metastasis,high recurrence,and drug resistance,so it is cru-cial to find specific molecular targets for the treatment of liver cancer.SLC7A11 is a key inhibitor of ferroptosis,promoting glutathione synthesis by mediating cystine uptake and protecting cells from oxidative stress damage.Recently,the biological effects of SLC7A11 on the occurrence and de-velopment of liver cancer,interventional embolization therapy,immunotherapy,radiation therapy,and targeted drug resistance have been reported.This paper gives a summary of this problem,aiming to provide new ideas and directions for molecular targeted therapy of liver cancer.
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