首页|夏橘化瘀胶囊治疗气虚血瘀型冠状动脉旁路移植术后再发心绞痛的临床效果

夏橘化瘀胶囊治疗气虚血瘀型冠状动脉旁路移植术后再发心绞痛的临床效果

扫码查看
目的 探讨夏橘化瘀胶囊治疗气虚血瘀型冠状动脉旁路移植术后再发心绞痛的临床效果.方法 选取2021年1月至12月山东省潍坊市中医院收治的70例行冠状动脉旁路移植术后再发心绞痛患者为研究对象,采用随机数字表法将其分为对照组和观察组,各35例.对照组采用西医常规治疗,观察组采用西医常规治疗+夏橘化瘀胶囊,两组均连续治疗3个月.比较两组中医证候疗效,比较两组治疗前后心绞痛发病频率、持续时间、西雅图心绞痛量表评分、N-末端B型利钠肽前体(NT-proBNP)、超敏C反应蛋白(hs-CRP)水平,同时记录患者相关安全性指标.结果 观察组中医证候疗效优于对照组(P<0.05).治疗后,两组心绞痛发病频率少于治疗前、持续时间短于治疗前,且观察组心绞痛发病频率少于对照组、持续时间短于对照组(P<0.05).治疗后,两组西雅图心绞痛量表各项评分均高于治疗前,且观察组高于对照组(P<0.05).治疗后,两组血清NT-proBNP、hs-CRP水平低于治疗前,且观察组低于对照组(P<0.05).两组不良反应发生率比较,差异无统计学意义(P>0.05).结论 夏橘化瘀胶囊对冠状动脉旁路移植术后再发心绞痛有明显改善作用,且安全性较高,具有重要的临床应用价值.
Clinical efficacy of Xiaju Huayu Capsules in treating recurrent angina pec-toris after coronary artery bypass grafting with qi deficiency and blood stasis type
Objective To explore the clinical effect of Xiaju Huayu Capsules in treating recurrent angina pectoris after coronary artery bypass grafting with qi deficiency and blood stasis type.Methods Seventy patients with recurrent angina pectoris after coronary artery bypass grafting ad-mitted to Weifang Traditional Chinese Medicine Hospital in Shandong Province from January to December 2021 were selected as the study subjects.They were divided into the control group and the observation group by random number table method,with 35 cases in each group.The control group received conventional western medicine treatment,while the observation group received conventional western medicine treatment+Xiaju Huayu Capsules.Both groups were treated continuously for three months.The therapeutic effect of traditional Chinese medicine syndromes was compared between two groups.The frequency and duration of angina pectoris,Seattle angina pectoris pectoris scale,N-terminal pro-B-type natriuretic pep-tide(NT-proBNP),and high-sensitivity C-reactive protein(hs-CRP)levels before and after treatment were compared between the two groups.Rel-evant safety indicators of the patients were also recorded.Results The therapeutic effect of traditional Chinese medicine syndrome in the observation group was better than that in the control group(P<0.05).After treatment,the angina frequency in both groups were less than before treatment,the duration in both groups were shorter than before treatment,the angina frequency pectoris in observation group was lower than that in the control group,the duration of observation group was shorter than that in the control group(P<0.05).After treatment,all scores on the Seattle angina pec-toris scale in both groups were higher than those before treatment,and the observation group was higher than the control group(P<0.05).After treatment,the serum NT-proBNP and hs-CRP levels in both groups were lower than those before treatment,and the observation group was low-er than the control group(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Xiaju Huayu Capsules has significant improvement effect on recurrent angina pectoris after coronary artery bypass grafting,and has high safety,which has important clinical application value.

Coronary heart diseaseAngina pectorisXiaju Huayu CapsulesCoronary artery bypass grafting

张立平、刘晓川、李杰、王霞、许军、张华涛

展开 >

山东省潍坊市中医院心内二科,山东潍坊 261031

冠心病 心绞痛 夏橘化瘀胶囊 冠状动脉旁路移植

山东省中医药科技重点项目

2020Z40

2024

中国医药导报
中国医学科学院

中国医药导报

CSTPCD
影响因子:1.759
ISSN:1673-7210
年,卷(期):2024.21(14)
  • 18