Discussion on the medication rule of Professor Wang Ziyu in the treat-ment of endometriotic disease based on data mining
Objective To investigate the medication rule of Professor Wang Ziyu in the treatment of endometriosis disease(EMD).Methods The prescription information of Professor Wang Ziyu from Dongzhimen Hospital,Beijing University of Chinese Medicine in treating EMD from January 2005 to December 2015 was collected.SPSS 20.0 and SPSS Modeler 18.0 software were used to analyze the frequency of drug use,four nature of drug,five flavours of drug,and channel tropism,and the common combinations of traditional Chinese medicine were analyzed according to system-atic clustering and association rule methods.Results A total of 502 traditional Chinese medicine prescriptions were collected,involving 132 kinds of traditional Chinese medicine,and the top 10 traditional Chinese medicine all had blood-activating effects.The drug nature of traditional Chinese medicine were mainly warm,flat,and slightly cold,and the drug flavours were bitter,pungent,and sweet,which were mostly returned to the liver and spleen channels.The high frequency traditional Chinese medicines were grouped into eight categories by cluster analysis.Association rule analysis showed that the known couplet medicines had strong correlation,and several unknown couplet medicines were discovered.A4 ngelicae Sinensis Radix-Paeoniae Radix Rubra-Salviae Miltiorrhizae Radix Et Rhizoma may be the core drug combination.The use of Wudan Pills in hospital was much more than other traditional Chinese patent medicines and simple preparations.Conclusion Professor Wang Ziyu's treatment of EMD is based on the core treatment of activating blood and eliminating disease,combining cold and warm,reinforcement and elimination in combi-nation.The clinical prescription is simple,the drug use is flexible,and he is good at matching activating blood drugs.
万方数据
维普
