Influencing factors of disease prognosis and construction of prediction model in patients with sepsis
Objective To explore the influencing factors of disease prognosis and construction of prediction model in patients with sepsis.Methods A total of 165 patients with sepsis treated in Lishui Central Hospital were enrolled from February to October 2021,according to 28 d prognosis,they were divided into good prognosis group(122 cases)and poor prognosis group(43 cases).The data of patients were collected.The influencing factors of disease prognosis in sepsis patients were analyzed by logistic regression equation,and the prediction model was constructed.The receiver opera-tor characteristic cure was drawn to analyze the predictive value of model.Results There were significant differences in oxygenation index,D-dimer(D-D),C-reactive protein(CRP),scores of sequential organ failure assessment(SOFA),and acute physiology and chronic health evaluation Ⅱ be-tween the two groups(P<0.05).Multivariate analysis showed that D-D(OR=2.195),CRP(OR=1.855),and SOFA score(OR=2.489)were inde-pendent risk factors of prognosis in sepsis patients(P<0.05),while oxygenation index(OR=0.571)was a protective factor of prognosis in sepsis pa-tients(P<0.05).The area under the receiver operator characteristic curve of oxygenation index,D-D,CRP,and SOFA score for the prognosis of sepsis was 0.825,0.785,0.721,and 0.834,respectively.Conclusion D-D,CRP,and SOFA score are independent risk factors of prognosis,while oxygenation index is protective factor in patients with sepsis.Clinically,targeted nursing based on these influencing factors is beneficial to improve prognosis of patients.
SepsisOxygenation indexD-dimerC-reactive proteinScore of sequential organ failure assessment