Mechanism and research progress of lncRNA TP73-AS1 regulating digestive system malignant tumors
Long non-coding RNA(lncRNA)are a class of non-coding transcripts that are more than 200 nucleotides long.lncRNA play an important regulatory role in the occurrence and development of cancer.Tumor protein P73 antisense RNA1(TP73-AS1)is a novel lncRNA,which is abnormally expressed in digestive system malignant tumors such as esophageal cancer,liver cancer,stomach cancer,and colorectal cancer,and is closely related to the occurrence and development of tumors,affecting the survival and prognosis of patients.This paper elucidates the mechanism and clinical significance of TP73-AS1 in gastrointestinal malignant tumors,and provides reference for future basic and clinical research.
Long non-coding RNATumor protein P73 antisense RNA1Digestive system malignant tumorsMechanism
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