Analysis of influencing factors for white blood cell count elevation after scoliosis surgery in children
Objective To investigate the influencing factors for white blood cell count(WBC)elevation after scoliosis surgery in children.Methods Clinical data of 81 children patients who underwent surgical treatment for scoliosis in Beijing Chao-Yang Hospital,Capital Medical University from January 2017 to July 2021 were collected,and according to whether WBC exceeded range of normal value,they were divided into normal group(29 cases)and elevated group(52 cases).General data and laboratory results were compared between two groups,single factor analysis was used to screen potential risk variables(P<0.2),and multivariate logistic regression model was used to analyze the influencing factors of postoperative WBC elevation.Results There were no significant differences in age,sex,body mass index,Cobb's angle of major thoracic curvature,preoperative hemoglobin level,living area,urine volume,blood loss,postoperative C-reactive protein level,postoperative hemoglobin level,and postoperative hospital stay between two groups(P>0.05).There were statistically significant differences in operation duration,intraoperative fluid volume,sub-group fluid volume,and postoperative blood platelet count between two groups(P<0.05).Cobb's angle of major thoracic curvature,operation dura-tion,subgroup fluid volume,and postoperative blood platelet count were influencing factors for postoperative WBC elevation(OR=0.973,1.012,0.129,1.023,P<0.05).Conclusion WBC elevation after scoliosis surgery in children may be closely related to the large Cobb's angle of major thoracic curvature,the prolonged operation time,subgroup fluid volume≤ 20 ml/(kg·h),and the increase of postoperative platelet count.