Impact of mitochondrial dysfunction on myocardial ischemia-reperfusion injury based on the theory of"deficiency qi stagnation"
This article explores the pathogenesis theory and traditional Chinese medicine treatment methods of myocardial ischemia reperfusion injury(MIRI)based on the theory of"deficiency qi stagnation"."Deficiency Qi"refers to the deficiency of essence and qi in the organs,resulting in disharmony of qi,blood,yin,and yang."stagnation"refers to the accumulation of various pathological products involved in the disease process."Deficiency Qi"is the pathological basis that leads to MIRI and is the foundation of its onset;"Stagnation"is the pathological key that leads to MIRI and is essential for its pathogenesis;the two are intertwined and mutually causal,ultimately forming a pathological state of"deficiency"and"stagnation",with"deficiency"as the foundation and"stagnation"as the standard,accompanied by"deficiency"and"stagnation".Therefore,this article is based on the basic theory of"deficiency qi stagnation"in traditional Chinese medicine,combined with mitochondrial dysfunction in modern medical mechanisms,to explore the correlation between the two in MIRI,comprehensively interpret the scientific connotation of the pathogenesis of"deficiency qi stagnation",and provide new ideas and theoretical basis for the prevention and treatment of MIRI in traditional Chinese medicine.
Myocardial ischemia reperfusion injuryMitochondrial functionDeficiency qi stagnationTraditional Chinese medicine