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五苓散现代临床应用及作用机制研究进展

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五苓散是治疗阳不化气、水湿内停的经典方剂,出自医圣张仲景的《伤寒杂病论》,该方组方严谨,配伍精当,常被古今医家加减化裁治疗各种疾病,其应用范围不断扩大。随着对经方的重视,五苓散被广泛应用于心血管系统、神经系统、消化系统、泌尿系统、呼吸系统和内分泌系统等疾病,均有较好疗效。五苓散具有抗炎、抗氧化应激、抗细胞凋亡、保护脑组织、恢复肠道菌群、抗肾间质纤维化及调节水液、脂质和尿酸代谢等作用。本文旨在对五苓散的临床应用及作用机制进行现代文献梳理及总结。
Research progress on clinical application and mechanism of Wuling San
Wuling San is a classic formula for treating yang's failure to transform qi and the internal suspension of water-dampness,which comes from Shanghan Zabing Lun by the medical sage Zhang Zhongjing.The formula is rigorous and well-matched,and it is often used by ancient and modern medical practitioners in the treatment of various diseases,and the scope of its application has been expanding continuously.With the emphasis on the prescription,Wuling San has been widely used in cardiovascular system,nervous system,digestive system,urinary system,respiratory system,endocrine system,and other diseases,which have better therapeutic effects.Wuling San has anti-inflammatory,anti-oxidative stress,anti-apoptosis,protection of brain tissue,restoration of intestinal flora,anti-renal interstitial fibrosis,regulation of water,lipid and uric acid metabolism.This article aims to conduct modern literature review and summary of clinical application and mechanism of action of Wuling San.

Wuling SanClinical applicationMechanismResearch progress

周晓洁、黄思雨、王一帆、张琳琪

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河南中医药大学第一附属医院肾病科,河南郑州 450000

河南中医药大学第一临床医学院,河南郑州 450046

五苓散 临床应用 作用机制 研究进展

国家自然科学基金资助项目国家中医药管理局第七批全国老中医药专家学术经验继承工作

81973806国中医药人教函[2022]76号

2024

中国医药导报
中国医学科学院

中国医药导报

CSTPCD
影响因子:1.759
ISSN:1673-7210
年,卷(期):2024.21(21)