Objective To analyze relevant research literature of Panax notoginseng saponins,grasp its development history,research hotspots,and development trends.Methods All Chineses literatures and English literatures related to Panax noto-ginseng saponins in CNKI,VIP,Wanfang Data,Chinese Biomedical Literature,and Web of Science core collection database from inception to April 2024 were retrieved.Publication volume,journal sources,authors,research institutions,and key-words were analyzed by using VOSviewer 1.6.20,CiteSpace 6.3.R1,Pajek 64 5.18,and NoteExpress 3.8.Results Finally,2 010 Chinese literatures were included,of which 1 703 were journal papers,307 were degree papers,and 280 were English literatures.Overall annual publication volume showed a fluctuating upward trend.Chinese literature was mainly published in Chinese Journal of Traditional Chinese Medicine,Chinese Journal of Experimental Formula Studies,Chinese Herbal Medicine,etc.English literature was mainly published in Acta Pharmacologic a Sinica,Journal of Ethnopharmacology,etc.There were a total of 4 410 Chinese literature authors and 1 476 English literature authors.Deng Changqing and ZHANG W had the highest number of publications in both Chinese and English,respectively.Beijing University of Chinese Medicine ranked first in both Chinese and English publications,collabo-rated with multiple institutions to form a cross regional and in-fluential scientific research academic group.The analysis of key words in Chinese literature and English literature showed that apoptosis,oxidative stress,cerebral hemorrhage,and reperfusion injury were the popular directions for Panax notoginseng sap-onins.Conclusion The research content of Panax notoginseng saponins is extensive and belongs to a popular focus of attention in the discipline.Many scholars are still deeply exploring its value and mechanism of action in treating diseases.The molec-ular mechanism mainly focuses on the pathways of apoptosis and oxidative stress.The treatment of cerebral hemorrhage and reperfusion injury is currently a hot research topic.
Panax notoginseng saponinsNotoginseng Radix Et RhizomaCiteSpaceVOSviewerVisual analysis
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