Mediating effects of sleep quality between frailty and depression in middle-aged and elderly diabetic patients
Objective To explore the mediating effects of sleep quality between frailty and depression in middle-aged and elderly diabetic patients.Methods The data from the fifth national follow-up of the China Health and Retirement Longitudinal Study conducted by Peking University in 2020 were used,880 middle-aged and elderly diabetic patients aged≥45 years were selected.Descriptive and Spearman correlation analysis were performed using SPSS 27.0,and the mediating effect was tested using the PROCESS macro.Results The depression score of middle-aged and elderly diabetic patients was 7.5(3.0,14.0)points,and the frailty index was 22.7(17.3,28.0).Female,older age,rural residence,current smoking,drinking alcohol at least once a month in the past year,and having a history of falls were associated with higher depression scores(P＜0.05).Depression was positively correlated with frailty(r=0.757,P＜0.01),and negatively correlated with sleep quality(r=-0.722,P＜0.01).Frailty was negatively correlated with sleep quality(r=-0.570,P＜0.01).Frailty directly affected depression in middle-aged and elderly diabetic patients(β=0.562,t=30.143,P＜0.001),and also indirectly affected depression through the mediating role of sleep quality,with the indirect effect accounting for 28.558％of the total effect.Conclusion Sleep quality is a mediating variable between frailty and depression in middle-aged and elderly diabetic patients.It is necessary to strengthen the prevention and comprehensive intervention of sleep quality issues in this population.
Middle-aged and elderly diabetes mellitusFrailtySleep qualityDepressionMediating effect
万方数据
维普
