首页|应用静脉-动脉体外膜肺氧合成人患者预防肢体缺血的证据总结

应用静脉-动脉体外膜肺氧合成人患者预防肢体缺血的证据总结

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目的 检索、评价并总结应用静脉-动脉体外膜肺氧合(VA-ECMO)成人患者预防肢体缺血的最佳证据,为临床护理实践提供参考.方法 按照"6S"证据模型在国内外数据库自上而下进行证据检索,包括临床决策、指南、专家共识、证据总结、系统评价、meta分析、随机对照试验等,由3名研究员对文献质量进行独立评价、证据提取和证据汇总.检索时限为2014年6月30日至2024年6月30日.结果 共纳入13篇文献,其中指南2篇,临床决策1篇,专家共识5篇,系统评价4篇,随机对照试验1篇,从血管选择、导管选择、设备管理、血压和体温管理、抗凝管理、早期监测与评估、分级管理等7个方面汇总了 21条证据.结论 该研究总结了应用VA-ECMO成人患者预防肢体缺血的最佳证据,可为医护人员针对VA-ECMO肢体缺血并发症的预防实施科学有效的规范化管理提供依据.
Evidence summary of preventing limb ischemia for adult patients with venoarterial extracorporeal membrane oxygenation
Objective To search,evaluate,and summarize the best evidence for preventing limb ischemia for adult patients with venoarterial extracorporeal membrane oxygenation(VA-ECMO),and to provide reference for clinical nursing practice.Methods According to"6S"evidence model,clinical decisions,guidelines,expert consensuses,evidence summaries,systematic reviews,meta-analysis,and randomized controlled trials for preventing limb ischemia for adult patients with VA-ECMO were top-down searched by computer in domestic and international databases.Three researchers independently appraised articles and extracted data for eligible studies.The retrieval period was from June 30,2014 to June 30,2024.Results A total of 13 articles were enrolled,including two guidelines,one clinical decision,five expert consensuses,four systematic reviews,and one randomized controlled trial.Totally 21 items of best evidence were summarized from seven aspects:vascular selection,catheter selection,device management,blood pressure,and temperature management,anticoagulation management,early monitoring and evaluation,and categorization management.Conclusion This study summarizs the best evidence on the application of VA-ECMO in adult patients for the prevention of limb ischemia,which can provide evidence-based references for medical staff to implement scientifically and effectively standardized management of the prevention of limb ischemia complications of VA-ECMO.

Venoarterial extracorporeal membrane oxygenationAdult patientsLimb ischemiaEvidence summaryEvidence-based nursing

王冰寒、蒙斯雅、韩建强、刘宇亭、霍晓旭、祁梦莹

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华中科技大学协和深圳医院深圳市南山区人民医院重症医学科,广东深圳 518000

静脉-动脉体外膜肺氧合 成人患者 肢体缺血 证据总结 循证护理学

2024

中国医药导报
中国医学科学院

中国医药导报

CSTPCD
影响因子:1.759
ISSN:1673-7210
年,卷(期):2024.21(23)