Hyperbaric oxygen therapy has shown remarkable antitumour effects in antitumour therapy by overcoming hypoxic microenvironment of tumours and improving their oxygenation status,often combined with radiochemotherapy.This paper reviews the application of hyperbaric oxygen therapy in adjuvant antitumour therapy,which not only sensitizes the effect of radiochemotherapy and alleviates the adverse reactions caused by radiochemotherapy,but also improves the therapeutic efficiency by combining with photodynamic therapy and nanomedicines.Hyperbaric oxygen therapy also plays an important role in toxicity management of antitumour therapy,such as improving cancerous skin injury and reducing the rate of skin flap defects after breast-conserving surgery.In the future,research and application of hyperbaric oxygen therapy in the treatment of tumours of different categories and degrees of malignancy still need to be further deepened in order to explore its maximum efficacy and safety.
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