Professor Liang Xiaochun's experience in the treatment of diabetic microvascular complications
Objective To investigate the medication rule of Professor Liang Xiaochun in the treatment of diabetic microvas-cular complications.Methods A retrospective real-world study method was used,with the electronic medical records from the hospital information system of Peking Union Medical College Hospital as the carrier.Clinical information of patients treated for diabetic microvascular complications by Professor Liang Xiaochun from January 2021 to December 2022 was col-lected to construct a database,which was then entered into the Traditional Chinese Medicine Inheritance Platform(V 3.5).Techniques such as association rule mining and cluster analysis were used to analyze the frequency of medication usage,the nature,flavour,and channel tropism of the medicines,and common drug combinations,the treatment principles and medica-tion patterns of Professor Liang Xiaochun for diabetic microvascular complications were summarized.Results A total of 301 effective prescriptions for treating diabetic microvascular complications by Professor Liang Xiaochun were collated,involving 211 Chinese herbal medicines.The most frequently used medicines were Mori Cortex,Cuscutae Semen,Commelina com-munis,Fructus Ligustri Lucidi,Euonymus alatus,Achyranthes aspera,etc.The four natures were mostly cold,and the five flavours were mostly sweetness.The channel tropism belonged to the liver,spleen,and kidney.The core combinations of medicines identified through correlation analysis were Cuscutae Semen-Fructus Ligustri Lucidi,Cuscutae Semen-Achyranthes aspera,Cuscutae Semen-Commelina communis,Cuscutae Semen-Mori Cortex,Fructus Ligustri Lucidi-Achyranthes aspera,Achyranthes asp era-Smilacis Glabrae Rhixoma,Fructus Ligustri Lucidi-Mori Cortex,Fructus Ligustri Lucidi-Commelina communis.The four core prescrip-tions were obtained by cluster analysis:Fructus Ligustri Luci-di-Cuscutae Semen-Mori Cortex-Commelina communis-Eu-onymus alatus-Achyranthes aspera,Commelina communis-Mori Cortex-Radix Puerariae-Salvia miltiorrhiza-Cuscutae Semen-Fructus Ligustri Lucidi,Fructus Ligustri Luci-di-Commelina communis-Cuscutae Semen-Mori Cortex-Chuanxiong Rhizoma-Spatholobus Suberectus Dunn,Mori Cor-tex-Cuscutae Semen-Folium Nelumbinis-Commelina communis-Fructus Ligustri Lucidi-Chuanxiong Rhizoma.Conclu-sion Professor Liang Xiaochun treats diabetic microvascular complications with the main therapeutic principles of invigorat-ing blood circulation to remove blood stasis,clearing away phlegm to eliminate turbidity,and supplementing deficiencies to support the body's vital energy.
NETL
NSTL
万方数据
