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王笑民教授治疗乳腺癌处方用药规律探析

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目的 统计和收录王笑民教授治疗乳腺癌的病案,分析王教授诊治乳腺癌的思路及处方用药经验.方法 选择2023年3月至2024年3月就诊于首都医科大学附属北京中医医院肿瘤科门诊诊断明确的激素受体阳性乳腺癌术后患者,经筛选后采集数据录入中医传承辅助平台(V2.5),采用软件"统计报表"及"数据分析"功能进行数据挖掘,分析王教授治疗乳腺癌常用药物、性味归经、核心处方及用药规律.结果 共收集313首有效处方,涉及145味中药,出现频次排前3位分别为半枝莲、白花蛇舌草和黄芩.药物四气分布以寒、温、平为主;五味分布以甘、苦、辛常见;归经分布以肝、脾经为最多.最终得出5个药物核心组合及5首新处方,其中有重要临床意义的新处方2首.结论 王教授治疗乳腺癌术后患者主要从肝、脾入手,以疏肝健脾、清热解毒、软坚散结和引火归元治则为主.
Exploration and analysis on prescription medication rules of Professor Wang Xiaomin in the treatment of breast cancer
Objective To collect and record medical records of Professor Wang Xiaomin in the treatment of breast cancer,and analyze thoughts and prescription medication experience of Professor Wang's in the diagnosis and treatment of breast cancer.Methods Postoperative patients with hormone receptor positive breast cancer with definite diagnosis received treatment at Oncology Clinic of Beijing Hospital of Traditional Chinese Medicine,Capital Medical University from March 2023 to March 2024 were selected.After screening,data was collected and inputed into traditional Chinese medicine inheritance assistance platform(V2.5).The"statistical report"and"data analysis"functions in software were used for data mining.Commonly used drugs,medicinal properties,medicinal taste,meridian tropism,core prescriptions and medication rules of Professor Wang in the treatment of breast cancer were analyzed.Results A total of 313 effective prescriptions were collected,involved 145 traditional Chinese medicines.Top three in terms of frequency of occurrence were Scutellariae Barbatae Herba,Hedyotis and Scutellariae Radix.The distributions of four qi of medicines were mainly cold,warm and calm;the five flavors were commonly distributed as sweet,bitter and spicy;the distributions of meridians were most common in liver and spleen meridians.Finally,five core drug combinations and five new prescriptions were obtained,included two new prescriptions with significant clinical significance.Conclusion Professor Wang in the treatment of postoperative patients with breast cancer mainly from liver and spleen,and mainly focuses on soothing liver and strengthening spleen,clearing away heat and detoxification,softening firm and dissipating knot,and inducing fire to return to original.

Breast cancerWang XiaominData miningMedication experiencePrescription rules

薛娜、李欣、许炜茹、于明薇、程培育、雷勇、王笑民

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首都医科大学附属北京中医医院肿瘤科,北京 100010

北京中医药大学研究生院,北京 100029

乳腺癌 王笑民 数据挖掘 用药经验 组方规律

2024

中国医药导报
中国医学科学院

中国医药导报

CSTPCD
影响因子:1.759
ISSN:1673-7210
年,卷(期):2024.21(24)