Visual analysis of research literature on Coptidis Rhizoma treating insom-nia based on CiteSpace
Objective To review the research hotspot and development trend of Coptidis Rhizoma for insomnia based on CiteSpace.Methods The relevant literatures on the treatment of insomnia by Coptidis Rhizoma monomer and compound were retrieved from Web of Science Core Collection Database,Wanfang Data,VIP,and CNKI from inception to June 2024.CiteSpace V6.2.R6 software was used to summarize the data of the literatures on Coptidis Rhizoma monomer and compound for the treatment of insomnia from various perspectives,such as the total number of publications,author cooperation network,core institutions,keyword co-occurrence and clustering,time line,and emergence map,and draw a visual knowledge map according to the analysis results.Results A total of 1 587 articles in Chinese and 85 in English were included in this study,and the number of published papers showed a fluctuating trend.The Chinese and English literatures included 588 authors,201 authors,522 institutions,and 62 institutions,respectively.There were 182 and 249 keywords in both Chinese and English literatures,excluding keywords related to search strategy.The top three keywords in Chinese frequency were"data mining","syndrome differentiation and treatment",and"medication rule".The top three keywords in English frequency were"banxia xiexin decoction","alkaloids",and"huanglian jiedu decoction".Chinese and English keywords form 12 effective clusters respectively.Chinese literature cluster mainly discussed the treatment of insomnia combined with other comorbidities,data mining of insomnia,efficacy evaluation,and prescription analysis of insomnia.English literature clustering mainly discussed the mechanism of Chinese prescription,the composition analysis of Coptidis Rhizoma monomer and compound,and the treatment of insomnia combined with other diseases.Key words time line and analysis of emergent results suggested that clinical observation,experience summary,data mining and basic experiment were common research methods for treating insomnia with Coptidis Rhizoma monomer and compound in this field,and intervention methods included traditional Chinese medicine monomer,traditional Chinese medicine compound,acupuncture and drug combination,etc.Conclusion The research on Coptidis Rhizoma monomer and compound for insomnia is on the rise,but the communication and cooperation between research teams need to be strengthened.At present,the research methods(clinical efficacy observation,clinical experience summary,data mining,basic experiments)are the research hotspots,and the research trends are efficacy evaluation,mechanism research and application of modern technology to improve the bioavailability of traditional Chinese medicine.