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针刺十三鬼穴理论渊源及神经生物学作用机制探讨

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十三鬼穴最早记载于唐代孙思邈《备急千金要方》,用于治疗以"鬼病"之称的癫狂症,后世发展成为治疗各类情志病的经验效穴。针刺十三鬼穴体现孙思邈"必通十二经脉""治道阴阳""荡涤五脏六腑""精神内守"的养病与针灸学术思想。目前,已证实针刺十三鬼穴可通过神经生物学机制有效治疗焦虑和抑郁障碍、失眠、脑卒中后功能障碍等疾病,但相关机制的系统总结鲜有报道。本文旨在探讨十三鬼穴理论渊源及其干预疾病的神经生物学作用机制,以期为十三鬼穴的现代应用提供思路。
Discussion on theoretical origin and neurobiological mechanism of acupuncture at thirteen ghost points
Thirteen ghost points are first recorded in Beiji Qianjin Yao Fang of Sun Simiao in Tang Dynasty,which is used to treat mania known as"ghost disease".Later generation,it has become an empirical acupoint selection in the treatment of various emotional diseases.Acupuncture at thirteen ghost points reflects recuperation and acupuncture and moxibustion academic thought of Sun Simiao,which include"smoothing twelve meridians","yin and yang principle-based medicine","harmonizing internal organs",and"preserving steady spirit".At present,it has been confirmed that acupuncture at thirteen ghost points can effectively treat anxiety disorder,depression disorder,insomnia,post-stroke dysfunction,and other diseases through neurobiological mechanisms,but systematic summary of related mechanisms is rarely reported.This paper focuses on theoretical origin of thirteen ghost points as well as neurobiological mechanisms of its intervention in diseases,in order to provide ideas for modern application of thirteen ghost points.

AcupunctureThirteen ghost pointsSun SimiaoNeurobiologyMechanism of action

张儒奇、董晓婕、朱炳旭、王盛春

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山东中医药大学针灸推拿学院,山东济南 250355

湖北中医药大学针灸骨伤学院,湖北武汉 430065

济宁医学院临床医学院,山东济宁 272067

山东第一医科大学附属省立医院针灸理疗康复科,山东济南 250021

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针刺 十三鬼穴 孙思邈 神经生物学 作用机制

山东省卫生健康委员会齐鲁医派中医学术流派传承项目山东省中医药科技发展计划项目山东省卫生健康委员会齐鲁卫生与健康领军人才培育工程项目

鲁卫函[2020]132号2019-0312鲁卫人字[2020]3号

2024

中国医药导报
中国医学科学院

中国医药导报

CSTPCD
影响因子:1.759
ISSN:1673-7210
年,卷(期):2024.21(26)