Research progress on modern clinical application and action mechanism of Xuefu Zhuyu Decoction
Xuefu Zhuyu Decoction is derived from Yilin Gaicuo written by Wang Qingren,a medical practitioner in Qing Dynasty.It has the effects of promoting blood circulation and removing blood stasis,as well as relieving pain through qi movement.It is mainly used for treating chest blood stasis syndrome,and is widely applied to various diseases with clinical symptoms of qi stagnation and blood stasis,achieving significant results.This article reviews literature from two aspects:modern clinical application and action mechanism of Xuefu Zhuyu Decoction.It explains that Xuefu Zhuyu Decoction is widely used in clinical treatment of cardiovascular diseases,neurological diseases,surgical diseases,ophthalmic diseases,obstetrics and gynecology diseases and endocrine diseases,all of which have achieved good results.At the same time,action mechanism of Xuefu Zhuyu Decoction in the treatment of diseases may be related to inhibition of inflammatory response,mitochondrial quality control,regulation of angiogenesis,reduction of oxidative stress and anti-fibrosis mechanisms.
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