Correlation study of residual cholesterol and arteriosclerosis in elderly health examination population
Objective To explore the correlation between residual cholesterol(RC)and arteriosclerosis(AS)in elderly healthy physical examination population.Methods A retrospective analysis was performed on 1 013 elderly people who un-derwent physical examination in the First Affiliated Hospital of Wannan Medical College from June to October 2023,and the degree of arterial injury was measured according to arm and ankle artery pulse wave conduction velocity(baPWV).Accord-ing to the baPWV measurement results,the physical examination population was divided into AS group(baPWV ≥ 1 400 cm/s)and non-AS group(baPWV＜1 400 cm/s).The Spearman rank correlation analysis was used to explore the association of RC and other risk factors for AS onset,and the binary logistic regression analysis(forward method)was used to explore the influencing factors of the incidence of AS in the elderly health examination population.Results Spearman Rank correlation analysis showed that RC was positively associated with hypertension,fasting Plasma Glucose,triglyceride,globulin,aspartate aminotransferase,aspartate aminotransferase/alanine transami-nase(rs=0.080,0.070,0.475,0.196,0.122,0.085,P＜0.05);and negatively associated with high density lipoprotein choles-terol,albumin/globulin(rs=-0.093,-0.170,P＜0.05).Binary logistic regression analysis showed that high RC level(OR=1.453,95％CI=1.024-2.061),hypertension(OR=2.071,95％CI=1.493-2.872),white blood cell count(OR=1.106,95％CI=1.012-1.208),pulse pressure difference(OR=1.018,95％CI=1.007-1.028),aspartate aminotransferase/alanine aminotransferase(OR=1.771,95％CI=1.303-2.406)were independent risk factors for AS in the elderly healthy population.High density lipoprotein cholesterol(OR=0.386,95％CI:0.255-0.583)was a protective factor for AS in the elderly healthy population.Conclusion The occurrence of AS in elderly healthy physical examination population is related to high RC level,and the incidence of AS can be reduced by monitoring RC level.
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