首页|中医药调控Keap1/Nrf2信号通路治疗肝癌的研究进展

中医药调控Keap1/Nrf2信号通路治疗肝癌的研究进展

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肝癌是全球常见的恶性肿瘤之一,发生率和死亡率居高不下.目前治疗肝癌的方法效果不佳,且有许多不良反应.Keap1/Nrf2信号通路是目前肝癌预防、诊断和治疗的研究热点.中医药通过调控Keap1/Nrf2信号通路治疗肝癌具有靶点多、副作用小、综合治疗等独特优势.本文对中医药通过Keap1/Nrf2信号通路治疗肝癌的研究进展进行综述,以期为中医药防治肝癌提供参考.
Research progress on traditional Chinese medicine and pharmacy regulating Keap1/Nrf2 signaling pathway in the treatment of liver cancer
Liver cancer is a prevalent malignant tumor globally with high incidence rate and mortality.The current methods in the treatment of liver cancer are ineffective,and have many adverse reactions.Keap1/Nrf2 signaling pathway is currently a research hotspot in the prevention,diagnosis,and treatment of liver cancer.Traditional Chinese medicine and pharmacy has unique advantages in the treatment of liver cancer by regulating Keap1/Nrf2 signaling pathway,including multiple targets,minimal side effects,and comprehensive treatment.This article reviews research progress on traditional Chinese medicine and pharmacy in the treatment of liver cancer through Keap1/Nrf2 signaling pathway,in order to provide reference for the prevention and treatment of liver cancer with t traditional Chinese medicine and pharmacy.

Keap1/Nrf2 signaling pathwayTraditional Chinese medicine and pharmacyLiver cancer

叶一娴、杜沅沁、赵雅然、彭倩、韦燕飞

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广西中医药大学基础医学院,广西南宁 530200

广西中医药大学第一临床医学院,广西南宁 530022

Keap1/Nrf2信号通路 中医药 肝癌

2025

中国医药导报
中国医学科学院

中国医药导报

影响因子:1.759
ISSN:1673-7210
年,卷(期):2025.22(9)