Expert Consensus on the Selection and Pharmaceutical Care of Perioperative Hemostatic Drugs
Objective This consensus aims to further standardize the rational use of hemostatic drugs in the perioperative period.Methods The study design of the consensus followed the World Health Organization guideline development handbook.Initially,common questions regarding the application of perioperative hemostatic drugs were systematically searched and collected.The Delphi method was then used to determine the clinical questions to be included.Subsequently,a secretariat team conducted a systematic literature search to comprehensively evaluate existing original research,systematic reviews,and related guidelines or expert consensus.Quality evaluation was performed according to the Grading of Recommendations Assessment,Development and Evaluation(GRADE)system.Finally,consensus on recommendation opinions and evidence levels was reached again through the Delphi method,resulting in the"Expert Consensus on the Selection and Pharmaceutical Care of Perioperative Hemostatic Drugs".Results During the consensus development process,assessment opinions on 31 clinical questions from 22 experts in the fields of clinical pharmacy,medicine,laboratory medicine,evidence-based medicine,hospital management,and health economics were collected through questionnaires.Ultimately,based on expert opinions,21 clinical questions were included,and 16 clinical medication recommendations were developed under the direction of the writing expert group and the supervision of the review expert panel.Conclusion This consensus comprehensively evaluates the efficacy and safety of 20 hemostatic drugs across 8 major categories during the perioperative period,providing clear guidance for healthcare professionals.
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维普
