医药导报2025,Vol.44Issue(1) :131-133.DOI:10.3870/j.issn.1004-0781.2025.01.018

丙泊酚致过敏性休克死亡1例

A Case of Anaphylactic Shock and Death Caused by Propofol

李晓东 彭芳 杨丹
医药导报2025,Vol.44Issue(1) :131-133.DOI:10.3870/j.issn.1004-0781.2025.01.018

丙泊酚致过敏性休克死亡1例

A Case of Anaphylactic Shock and Death Caused by Propofol

李晓东 1彭芳 1杨丹2
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作者信息

  • 1. 安宁市第一人民医院药学部,昆明 650300
  • 2. 昆明市药品不良反应与药物滥用监测中心,昆明 650000
  • 折叠

摘要

患者,女,48岁,因子宫内节育器取出手术麻醉给予丙泊酚乳状注射液100 mg,静脉注射,发生过敏性休克死亡.采用诺氏评分法判断怀疑药品致过敏性休克死亡相关性,结合相关文献分析丙泊酚导致过敏的作用机制,警戒临床关注丙泊酚的安全性,并为避免使用丙泊酚出现过敏性休克提出了可行建议.

Abstract

The patient,female,48 years old,died of anaphylactic shock due to anesthesia with an intravenous injection of 100 mg propofol emulsion injection in the removal surgery of the intrauterine device.We used the Norris scoring method to determine the association between suspected drug,anaphylactic shock,and death,combined with relevant literature analysis of the mechanism of propofol-induced allergy,to alert clinical attention to the safety of propofol.We proposed feasible suggestions to avoid the occurrence of anaphylactic shock caused by propofol.

关键词

丙泊酚/过敏性休克/死亡/药品不良反应

Key words

Propofol/Anaphylactic shock/Death/Adverse reaction

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出版年

2025
医药导报
中国药理学会 华中科技大学同济医学院附属同济医院 中国医药商业协会

医药导报

CSTPCD北大核心
影响因子:1.042
ISSN:1004-0781
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