Objective To investigate the relationship between related blood biomarkers and progressive atherosclerotic restenosis after stent implantation for intracranial artery stenosis.Methods A total of 140 patients who underwent stenting for intracranial artery stenosis in our hospital from January 2020 to August 2022 were selected for the study.The occurrence of recurrent ischemic cerebrovascular events after symptomatic intracranial artery stenosis stenting during the 12-month postoperative follow-up period was counted and classified into recurrent/ischemic stroke(n=15)and non-recurrent/ischemic stroke(n=125).Statistical analysis of biological indicators and symptoms during the follow-up period was performed.Results In univariate analysis,mean platelet volume was associated with recurrent/ischemic events(p<0.05).Multiple logistic regression analysis suggested that in-stent restenosis(ISR)was a significant risk factor for recurrent/ischemic stroke.Conclusions ISR is an important risk factor for the development of recurrent stroke or transient ischemic attack,and blood biomarkers tested after surgery are positively associated with ISR.
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