Objective To develop an intelligent closed-loop management system for intravenous drugs in outpatient hemodialysis patients and evaluate its application effect.Methods Taking the management of intravenous drugs for outpatients with hemodialysis in a tertiary hospital in Ningbo as an example,a multidisciplinary and multi-department team was established to analyze the defects in the process of intravenous drugs for outpatients with hemodialysis,and an intelligent closed-loop management system for intravenous drugs for outpatients with hemodialysis was designed.Results After the application of the intravenous drug system in outpatient hemodialysis patients,the intravenous drug dispensing time of outpatient hemodialysis patients was 55±5.13 minutes,and the incidence of adverse events related to the medication process was reduced to l.01‰.Conclusion The intelligent closed-loop management of intravenous drugs in outpatient hemodialysis patients can shorten the dispensing time and reduce the incidence of adverse events related to the process.At the same time,the system has been well recognized in terms of user-friendly interface and improving medical and nursing satisfaction,and the clinical effect is significant,which is worthy of promotion and application.