Application Value of Two-Dimensional Speckle Tracking Echocardiography in Evaluating Right Ventricle Func-tion in Patients with Pulmonary Arterial Hypertension Secondary to Rheumatoid Arthritis-Associated Interstitial Lung Disease
Objective To explore the applicability of two-dimensional speckle-tracking echocardiography(2D-STE)in as-sessing right ventricle function in patients with pulmonary arterial hypertension(PAH)secondary to rheumatoid arthritis-as-sociated interstitial lung disease(RA-ILD).A total of 56 RA-ILD patients treated in the People's Hospital,Hubei Universi-ty of Medicine from January 2022 to June 2023 were divided into groups based on their pulmonary artery systolic pressure(PASP):mild(17 cases),moderate(14 cases),and severe(10 cases).A control group comprised 15 RA-ILD patients with normal pulmonary artery pressure.Right ventricle echocardiographic parameteres,including tricuspid annular plane sys-tolic excursion(TAPSE),tricuspid annular peak systolic velocity(Sm),right ventricular fractional area change(RVFAC),right ventricular myocardial performance index(RMPI),and right ventricular free wall longitudinal strain(RVLSFw)were measured.Differences in these indices among the groups were analyzed.Results Compared with the conditions in the control group,no significant differences were observed in TAPSE,Sm,RVFAC,and RMPI in the mild group(all P＞0.05),while RVLSFw showed a reduction(P＜0.05).A gradual increase in RMPI and a decrease in TAPSE,Sm,RVFAC,and RVLSFw were noted from mild to severe groups,with significant intergroup differences(all P＜0.05).Pearson correlation analysis revealed a positive correlation between RVLSFw and RMPI and a negative correlation with TAPSE,RVFAC,and Sm.ROC curve demonstrated that RVLSFw possesses high diagnostic efficacy in evaluating declining markers of right ventri-cle function.Conclusion 2D-STE facilitates the early detection of changes in the systolic function of the right ventricle in PAH patients due to RA-ILD,supporting its significant role in the clinical assessment and prognosis of affected patients.
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