Effect of Mirror Therapy Combined with Repetitive Transcranial Magnetic Stimulation on Upper Limb Function After Stroke
Objective To explore the rehabilitation effect of mirror therapy(MT)combined with repetitive transcranial mag-netic stimulation(rTMS)on upper limb motor dysfunction after stroke.Methods A total of 68 newly diagnosed stroke pa-tients admitted to the Department of Rehabilitation Medicine,Xiangyang No.1 People's Hospital,Hubei University of Medi-cine from December 2021 to June 2023 were selected.They were randomly divided into a control group,MT group,rTMS group,and combination group.The control group received routine rehabilitation treatment after stroke,3～4 h/d,6 d/week,for 4 weeks in total.The MT group and the rTMS group received additional MT therapy and 5 Hz rTMS therapy,re-spectively after routine rehabilitation treatment.The combination group was treated with MT therapy and rTMS therapy on the basis of the control group.The four groups were evaluated using the simplified Fugl-Meyer Assessment Upper Extremity(FMA-UE)and modified Barthel Index(MBI)before and 4 weeks after treatment.The cortical latency(CL)and central motor conduction time(CMCT)of the affected brain area were also measured.Results A total of 65 patients completed the trial,with 2 cases of dropout in the MT group and 1 case of dropout in the combination group.After treatment,the FMA-UE and MBI scores of the four groups were improved compared with those before treatment(P＜0.05),and the MT group,rTMS group,and the combination group were better than the control group,with the combination group achieving the opti-mal results(P＜0.05).Compared with the conditions before treatment,the CL and CMCT of the four groups were reduced(P＜0.05);the MT group,rTMS group and combination group were lower than the control group,with the combination group having the lowest results(P＜0.05).Conclusion Both MT and rTMS can improve the excitability and upper limb mo-tor function of the affected cerebral cortex of stroke patients.Early treatment with combined MT and rTMS has a desirable effect on improving the upper limb motor function of the affected side.
Mirror therapyRepetitive transcranial magnetic stimulationStrokeUpper limb motor functionRehabilita-tion training
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