Effects of oyster peptide and phytic acid on mineral absorption and bioavailability in rats
To explore the effects of oyster peptide and phytic acid on mineral absorption and bioavailability in vivo,Wistar rats were fed with a normal diet and a 1％phytic acid diet respectively,and supplemented with low,medium,and high doses(0.5,1.2,and 2.0 g/kg·bw)of oyster peptides for 6 weeks.The apparent absorption rates of Fe,Zn,Ca,Mg,as well as their content in serum,liver,and bones were measured.The results showed that:phytic acid diet significantly reduced the apparent absorption rates of Fe,Zn,Ca,and Mg,while supplementation with oyster peptides significantly increased these apparent absorption rates in a dose-dependent manner,effectively reversing the reductions induced by phytic acid.The phytic acid diet re-duced the bioavailability of mineral elements such as Fe,Zn,Ca,and Mg in body tissues,while supplementa-tion with oyster peptides increased the bioavailability of Fe and Zn in the liver,promoted the transfer of Ca and Mg from the liver,and increase the deposition of Fe,Ca,and Mg in bones.The research shows that oyster peptide supplementation not only significantly promotes the absorption and bioavailability of mineral elements such as Fe and Zn in rats on a normal diet rats,but also partially reverses the absorption and bioavailability barriers of mineral elements induced by phytic acid diet.
万方数据
维普
