In the face of the opportunity brought by intelligence for innovation and development,the data of listed company in the manufacturing industry from 2012 to 2019 were used to study the impact of intelligence on the innovation performance of manufacturing enterprise.The research shows that intelligence promotes the innovation performance of manufacturing enterprise to improve significantly,which is reflected in both quantity and quality,and helpful to improve the structural innovation momentum and improve the core innovation competitiveness.Further analysis confirms that R&D efficiency,R&D investment intensity,human capital allocation,and government subsidy are important ways that intelligence improves the innovation performance of manufacturing enterprise.The innovation performance of large enterprise,high-tech industry enterprise,and non-state-owned enterprise has benefited more under the influence of intelligence,and has obvious scale bias and technical background dependence.