Consensus statement on research and application of Chinese herbal medicine derived extracellular vesicles-like particles(2023 edition)

Qing Zhao ¹Tong Wang ²Hongbin Wang ³Peng Cao ⁴Chengyu Jiang ⁵Hongzhi Qiao ⁶Lihua Peng ⁷Xingdong Lin ¹Yunyao Jiang ⁸Honglei Jin ⁹Huantian Zhang ¹⁰Shengpeng Wang ¹¹Yang Wang ¹²Ying Wang ¹³Xi Chen ¹⁴Junbing Fa ¹³Bo Li ¹⁵Geng Li ¹⁶Bifeng Liu ¹⁷Zhiyang Li ¹⁸Suhua Qi ¹⁹Mingzhen Zhang ²⁰Jianjian Zheng ²¹Jiuyao Zhou ³Lei Zheng ²²Kewei Zhao¹

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作者信息

1. Guangdong Engineering Research Center of Chinese Herbal Vesicles,The Third Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510378,China;Guangzhou Key Laboratory of Chinese Medicine Research on Prevention and Treatment of Osteoporosis,The Third Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510378,China
2. Institute of Life and Health Engineering,the First Affiliated Hospital,Jinan University,Guangzhou 510630,China
3. School of Pharmaceutical Sciences,Guangzhou University of Chinese Medicine,Guangzhou 510006,China
4. College of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210046,China;Guangdong Engineering Research Center of Chinese Herbal Vesicles,The Third Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510378,China;Guangzhou Key Laboratory of Chinese Medicine Research on Prevention and Treatment of Osteoporosis,The Third Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510378,China
5. Institute of Basic Medicine,Chinese Academy of Medical Sciences,Beijing 100005,China
6. College of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210046,China
7. College of Pharmaceutical Sciences,Zhejiang University,Hangzhou 310030,China
8. School of Pharmaceutical Sciences,Tsinghua University,Beijing 100084,China
9. School of Pharmaceutical Sciences,Guangzhou University of Chinese Medicine,Guangzhou 510006,China;Guangzhou Key Laboratory of Chinese Medicine Research on Prevention and Treatment of Osteoporosis,The Third Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510378,China
10. Department of Bone and Joint Surgery,The First Affiliated Hospital of Jinan University,Guangzhou 510630,China;Guangzhou Key Laboratory of Chinese Medicine Research on Prevention and Treatment of Osteoporosis,The Third Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510378,China
11. State Key Laboratory of Quality Research in Chinese Medicine,Institute of Chinese Medical Sciences,University of Macau,Aomen 999078,China
12. Shanghai Jiao Tong University Affiliated Sixth People's Hospital,Shanghai 200233,China
13. School of Basic Medical Sciences,Southern Medical University,Guangzhou 510515,China
14. School of Life Sciences,Nanjing University,Nanjing 210008,China
15. Nanfang Hospital,Southern Medical University,Guangzhou 510515,China
16. Laboratory Animal Center,Guangzhou University of Chinese Medicine,Guangzhou 510405,China
17. College of Life Science and Technology,Huazhong University of Science and Technology,Wuhan 430074,China
18. Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital,Nanjing 210008,China
19. School of Medical and Technology,Xuzhou Medical University,Xuzhou 221004,China
20. School of Basic Medical Sciences,Xi'an Jiaotong University,Xi'an 710065,China
21. The First Affiliated Hospital of Wenzhou Medical University,WenZhou 325035,China
22. Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;Guangdong Engineering Research Center of Chinese Herbal Vesicles,The Third Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510378,China;Guangzhou Key Laboratory of Chinese Medicine Research on Prevention and Treatment of Osteoporosis,The Third Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510378,China
折叠

Abstract

To promote the development of extracellular vesicles of herbal medicine especially the establishment of standardization,led by the National Expert Committee on Research and Application of Chinese Herbal Vesicles,research experts in the field of herbal medicine and extracellular vesicles were invited nation-wide with the support of the Expert Committee on Research and Application of Chinese Herbal Vesicles,Professional Committee on Extracellular Vesicle Research and Application,Chinese Society of Research Hospitals and the Guangdong Engineering Research Center of Chinese Herbal Vesicles.Based on the col-lation of relevant literature,we have adopted the Delphi method,the consensus meeting method com-bined with the nominal group method to form a discussion draft of"Consensus statement on research and application of Chinese herbal medicine derived extracellular vesicles-like particles(2023)".The first draft was discussed in online and offline meetings on October 12,14,November 2,2022 and April and May 2023 on the current status of research,nomenclature,isolation methods,quality standards and research applications of extracellular vesicles of Chinese herbal medicines,and 13 consensus opinions were finally formed.At the Third Academic Conference on Research and Application of Chinese Herbal Vesicles,held on May 26,2023,Kewei Zhao,convenor of the consensus,presented and read the consensus to the experts of the Expert Committee on Research and Application of Chinese Herbal Vesicles.The con-sensus highlights the characteristics and advantages of Chinese medicine,inherits the essence,and keeps the righteousness and innovation,aiming to provide a reference for colleagues engaged in research and application of Chinese herbal vesicles at home and abroad,decode the mystery behind Chinese herbal vesicles together,establish a safe,effective and controllable accurate Chinese herbal vesicle prevention and treatment system,and build a bridge for Chinese medicine to the world.

Key words

Chinese herbal medicine/extracellular vesicles/research application/consensus

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基金项目

National Science Foundation of China(82174119)

Young Talent Support Project of Guangzhou Association for Science and Technology(QT2023036)

Science and Technology Projects in Liwan District,Guangzhou(20230710)

Science and Technology Projects in Liwan District,Guangzhou(202201009)

Special Focus Areas for General Universities in Guangdong Province(2022ZDZX2016)

出版年

2024

中草药(英文版)

天津药物研究院中国医学科学院药用植物研究所

中草药(英文版)

CSTPCD

影响因子：0.6

ISSN：1674-6384

参考文献量53

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