Abstract
Ganoderma lucidum is a Chinese medicinal fungus with a long history of use in healthcare and disease treatment.G.lucidum spores(GLS)are tiny germ cells released from the mushroom cap during the mature stage of growth.They contain all the genetic active substances of G.lucidum.G.lucidum spore oil(GLSO)is a lipid component extracted from broken-walled Ganoderma spores using supercritical CO2 extraction technology.GLSO contains fatty acids,Ganoderma triterpenes,sterols and other bioactive compounds.Previous studies have demonstrated that GLSO has a wide range of pharmacological properties,including anti-tumor,anti-aging,neuroprotection,immunomodulation,hepatoprotection and modulation of meta-bolic diseases.This review summarizes the research progress of GLSO over the past two decades in terms of its bioactive components,extraction and processing techniques,pharmacological effects and safety evaluation.This provides a solid foundation for further research and application of GLSO.
基金项目
Pearl River S&T Nova Program of Guangzhou(201610010113)
Open Research Fund of NMPA Key Laboratory for Rapid Testing Technology of Drugs,Guangdong Institute for Drug Control(KF2022002)
Open Research Fund of NMPA Key Laboratory for Rapid Testing Technology of Drugs,Guangdong Institute for Drug Control(KF2022006)
Research Project of Chinese Medicine in TCM Bureau of Guangdong Province(20231202)
NETL
NSTL
万方数据