首页|Bioactive components,pharmacological properties and underlying mechanism of Ganoderma lucidum spore oil:A review

Bioactive components,pharmacological properties and underlying mechanism of Ganoderma lucidum spore oil:A review

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Ganoderma lucidum is a Chinese medicinal fungus with a long history of use in healthcare and disease treatment.G.lucidum spores(GLS)are tiny germ cells released from the mushroom cap during the mature stage of growth.They contain all the genetic active substances of G.lucidum.G.lucidum spore oil(GLSO)is a lipid component extracted from broken-walled Ganoderma spores using supercritical CO2 extraction technology.GLSO contains fatty acids,Ganoderma triterpenes,sterols and other bioactive compounds.Previous studies have demonstrated that GLSO has a wide range of pharmacological properties,including anti-tumor,anti-aging,neuroprotection,immunomodulation,hepatoprotection and modulation of meta-bolic diseases.This review summarizes the research progress of GLSO over the past two decades in terms of its bioactive components,extraction and processing techniques,pharmacological effects and safety evaluation.This provides a solid foundation for further research and application of GLSO.

anti-aginganti-tumorbioactive componentsGanoderma lucidum spore oilhepatoprotectionimmune regulationpharmacological properties

Jianying Liu、Binzhi Zhang、Leqi Wang、Shasha Li、Qinqiang Long、Xue Xiao

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Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine(Institute of Chinese Medicine),Guangdong Pharmaceutical University,Guangzhou 510006,China

The Second Clinical College of Guangzhou University of Chinese Medicine,Guangzhou Higher Education Mega Center,Guangzhou 510120,China

NMPA Key Laboratory for Rapid Testing Technology of Drugs,Guangdong Institute for Drug Control,Guangzhou 510525,China

Pearl River S&T Nova Program of GuangzhouOpen Research Fund of NMPA Key Laboratory for Rapid Testing Technology of Drugs,Guangdong Institute for Drug ControlOpen Research Fund of NMPA Key Laboratory for Rapid Testing Technology of Drugs,Guangdong Institute for Drug ControlResearch Project of Chinese Medicine in TCM Bureau of Guangdong Province

201610010113KF2022002KF202200620231202

2024

10.1016/j.chmed.2023.09.007

中草药(英文版)
天津药物研究院 中国医学科学院药用植物研究所

中草药(英文版)

CSTPCD
影响因子：0.6
ISSN：1674-6384
年,卷(期)：2024.16(3)