Biotransformation and pharmacological activities of platycosides from Platycodon grandiflorum roots

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外文摘要：In Northeast China,Goubao pickle is a popular food fermented from the roots of Platycodon grandiflorum as the main material,offering a unique flavor and rich nutritional value.Platycosides in roots of P.gran-diflorum may play a crucial role in determining the quality of Goubao pickle through microorganism fer-mentation.However,biotransfermation of platycosides has not been reviewed during fermentation.In this study,we reviewed platycosides in chemical diversity,metabolic processes in vivo,biotransformation of platycosides in vitro,and pharmacological effects.Finally,we also discussed how to improve the bioac-tive secondary platycosides we desire by regulating enzymes from microorganisms in the future.

外文关键词：

biotransformationGoubao picklemicroorganismspharmacological activitiesplatycosidesPlatycodon grandiflorum(Jacq.)A.DC

作者：

Lin Shi、Tong Cui、Xinyue Wang、Rina Wu、Junrui Wu、Yanqun Wang、Weiming Wang

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作者单位：

College of Food Science,Shenyang Agricultural University,Shenyang 110866,China

Institute of Chinese Materia Medica,Heilongjiang Academy of Chinese Medicine Sciences,Harbin 150036,China

基金：

National Natural Science Foundation of ChinaScientific Research Foundation of Heilongjiang Provincial Scientific Research InstitutesYoung and middleaged graduate tutor training program of Shenyang Agricultural University

项目编号：

U20A20400CZKYF2021A0022022-ZZDS-09

出版年：

2024

DOI：

10.1016/j.chmed.2024.01.004

中草药(英文版)

天津药物研究院中国医学科学院药用植物研究所

中草药(英文版)

CSTPCD

影响因子：0.6

ISSN：1674-6384

年,卷(期)：2024.16(3)