中草药(英文版)2024,Vol.16Issue(3) :392-400.DOI:10.1016/j.chmed.2024.01.004

Biotransformation and pharmacological activities of platycosides from Platycodon grandiflorum roots

Lin Shi Tong Cui Xinyue Wang Rina Wu Junrui Wu Yanqun Wang Weiming Wang
中草药(英文版)2024,Vol.16Issue(3) :392-400.DOI:10.1016/j.chmed.2024.01.004

Biotransformation and pharmacological activities of platycosides from Platycodon grandiflorum roots

Lin Shi 1Tong Cui 1Xinyue Wang 1Rina Wu 1Junrui Wu 1Yanqun Wang 1Weiming Wang2
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作者信息

  • 1. College of Food Science,Shenyang Agricultural University,Shenyang 110866,China
  • 2. Institute of Chinese Materia Medica,Heilongjiang Academy of Chinese Medicine Sciences,Harbin 150036,China
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Abstract

In Northeast China,Goubao pickle is a popular food fermented from the roots of Platycodon grandiflorum as the main material,offering a unique flavor and rich nutritional value.Platycosides in roots of P.gran-diflorum may play a crucial role in determining the quality of Goubao pickle through microorganism fer-mentation.However,biotransfermation of platycosides has not been reviewed during fermentation.In this study,we reviewed platycosides in chemical diversity,metabolic processes in vivo,biotransformation of platycosides in vitro,and pharmacological effects.Finally,we also discussed how to improve the bioac-tive secondary platycosides we desire by regulating enzymes from microorganisms in the future.

Key words

biotransformation/Goubao pickle/microorganisms/pharmacological activities/platycosides/Platycodon grandiflorum(Jacq.)A.DC

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基金项目

National Natural Science Foundation of China(U20A20400)

Scientific Research Foundation of Heilongjiang Provincial Scientific Research Institutes(CZKYF2021A002)

Young and middleaged graduate tutor training program of Shenyang Agricultural University(2022-ZZDS-09)

出版年

2024
中草药(英文版)
天津药物研究院 中国医学科学院药用植物研究所

中草药(英文版)

CSTPCD
影响因子:0.6
ISSN:1674-6384
参考文献量4
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