Lignans and flavonoids from rhizome of Drynaria fortunei
Objective To study the chemical constituents from the rhizome of Drynaria fortunei. Methods Silica gel, ODS,Sephadex LH-20 column chromatography, and semi-preparative HPLC were used to isolate pure compounds. The compounds were identified on the basis of their physicochemical properties and spectroscopic data. Results Fourteen compounds were isolated from the rhizome of D. fortunei, including three lignans (1-3) and eight flavonoids (4-11). By spectroscopic techniques, such as 1H-NMR, 13C-NMR, and ESI-MS, these compounds were identified as (7'R,8'S)-dihydrodehydrodiconiferyl alcohol 4'-O-β-D-glucopyranoside (1), lariciresinol 4'-O-β-D-glucopyranoside (2), (-)-secoisolariciresinol 4-O-β-D-glucopyranoside (3), eriodictyol (4), eriodictyol 7-O-β-D-glucopyranoside (5), neoeriocitrin (6), naringin (7), luteolin (8), luteolin 7-O-β-D-glucopyranoside (9),luteolin 8-C-β-D-glucopyranoside (10), 2',4'-dihydroxydihydrochalcone (11), maltol 3-O-β-D-glucopyranoside (12), β-sitosterol (13),and daucosterol (14). Conclusion Compounds 1-3, and 11 are isolated from the plants in Polypodiaceae family for the first time,and compounds 5 and 8-10 are isolated from the plants of Drynaria (Bory) J. Sm. for the first time. Compound 1 is present as rotamers at room temperature.
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