Lignans and triterpenoids from roots of Kadsura longipedunculata
Objective To study the chemical constituents from the roots of Kadsura longipedunculata.Methods The constituents were isolated and purified by various chromatographic methods,and the structures were identified on the basis of spectroscopic analysis.Results Fifteen compounds including 10 lignans and five triterpenoids were isolated from the roots ofK.longipedunculata and the structures were identified as (2S,3S)-4,4-bis (3,4-dimethoxyphenyl)-2,3-dimethyl-1-butanol (1),(2S,3S)-4,4-bis (4-hydroxy-3-methoxyphenyl)-2,3-dimethyl-1-butanol (2),kadangustin K (3),benzoyloxokadsuranol (4),propoxyloxokadsuranol (5),kadsutherin C (6),heteroclitin E (7),schiarisanrin C (8),heteroclitin J (9),kadsuphilin J (10),propindilactone J (11),kadcoccilactone C (12),kadsuphilactone B (13),wuweizidilactone D (14),and wuweizidilactone H (15).Conclusion All compounds are isolated from K.longipedunculata for the first time,and compounds 1,2,11,and 14 are isolated from the genus Kadsura Kaempf.ex Juss.for the first time,compounds 1 and 2 are new natural products.
Kadsura longipedunculata Finet et Gagneplignanstriterpenoidskadsutherin Cpropindilactone Jwuweizidilactone D